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A randomized controlled multimodal behavioral intervention trial for improving antiepileptic drug adherence

Overview of attention for article published in Epilepsy & Behavior, September 2015
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1 X user

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146 Mendeley
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Title
A randomized controlled multimodal behavioral intervention trial for improving antiepileptic drug adherence
Published in
Epilepsy & Behavior, September 2015
DOI 10.1016/j.yebeh.2015.08.036
Pubmed ID
Authors

Amir H. Pakpour, Maryam Gholami, Ravanbakhsh Esmaeili, Seyed Abolhasan Naghibi, John A. Updegraff, Gerard J. Molloy, Stephan U. Dombrowski

Abstract

Medication nonadherence is one of the most important reasons for treatment failure in patients with epilepsy. The present study investigated the effectiveness of a multicomponent intervention to improve adherence to antiepileptic drug (AED) medication in patients with epilepsy. In a prospective, randomized multicenter trial, three sessions of face-to-face motivational interviewing (MI) in combination with complementary behavior change techniques were compared with standard care. Motivational interviewing prompted change talk and self-motivated statements from the patients, planning their own medication intake regimen and also identifying and overcoming barriers that may prevent adherence. Participants were provided with calendars to self-monitor their medication taking behavior. A family member and the health-care team were invited to attend the last session of MI in order to improve the collaboration and communication between patients, their caregiver or family member, and their health-care provider. At baseline and 6-month follow-up, psychosocial variables and medical adherence were assessed. In total, 275 participants were included in the study. Compared with the active control group, patients in the intervention group reported significantly higher medication adherence, as well as stronger intention and perceptions of control for taking medication regularly. The intervention group also reported higher levels of action planning, coping planning, self-monitoring, and lower medication concerns. This study shows that MI can be effective in clinical practice to improve medication adherence in patients with epilepsy. It also provides evidence that combining volitional interventions, including action planning, coping planning, and self-monitoring with motivational interviewing can promote the effectiveness of the medical treatments for epilepsy by improving adherence.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 <1%
Unknown 145 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 24 16%
Researcher 17 12%
Student > Ph. D. Student 15 10%
Student > Doctoral Student 13 9%
Student > Bachelor 12 8%
Other 32 22%
Unknown 33 23%
Readers by discipline Count As %
Psychology 29 20%
Medicine and Dentistry 26 18%
Nursing and Health Professions 19 13%
Social Sciences 6 4%
Pharmacology, Toxicology and Pharmaceutical Science 6 4%
Other 20 14%
Unknown 40 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2015.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from Epilepsy & Behavior
#2,762
of 4,609 outputs
Outputs of similar age
#171,319
of 286,442 outputs
Outputs of similar age from Epilepsy & Behavior
#32
of 66 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,609 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,442 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.