| Title |
Some Elements in Thyroid Tissue are Associated with More Advanced Stage of Thyroid Cancer in Korean Women
|
|---|---|
| Published in |
Biological Trace Element Research, September 2015
|
| DOI | 10.1007/s12011-015-0502-5 |
| Pubmed ID | |
| Authors |
Hye-Kyung Chung, Ji Sun Nam, Chul Woo Ahn, Yong Sang Lee, Kyung Rae Kim |
| Abstract |
Excessive exposure to heavy metals including cadmium and lead is known to have adverse effects on various types of cancer. The aim of the present study was to evaluate the associations between blood and tissue levels of heavy metals and trace elements and different stages of thyroid cancer in Korean women. Ninety-two Korean women undergoing thyroidectomy were included in this study. Blood and thyroid tissue levels of cadmium, lead, mercury, selenium, and zinc were measured, and histopathological results, cancer tumor node metastasis (TNM) stage, and cancer multifocality were assessed. The tissue levels of cadmium, selenium, and zinc were significantly higher in patients with TNM stages 3 and 4 compared to those in stage 1. The tissue level of cadmium was greater in patients with higher tumor stage (≥T2) than those with lower stage (T1). Also, the tissue levels of cadmium and zinc were higher in multifocal group than in unifocal group. A logistic multiple regression analysis showed that the odds ratio (OR) for advanced tumor stage group (≥T2) increased in those with higher tissue cadmium level after adjustment (OR = 1.397, 95 % CI = 1.078-1.811). The accumulation of cadmium in thyroid tissue may be one of important etiologic factors for the thyroid cancer progression and aggravation in Korean women. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 40% |
| United States | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | 3% |
| Brazil | 1 | 3% |
| Unknown | 32 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 18% |
| Researcher | 4 | 12% |
| Student > Master | 3 | 9% |
| Student > Doctoral Student | 2 | 6% |
| Student > Postgraduate | 2 | 6% |
| Other | 7 | 21% |
| Unknown | 10 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 15% |
| Biochemistry, Genetics and Molecular Biology | 3 | 9% |
| Environmental Science | 2 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
| Nursing and Health Professions | 2 | 6% |
| Other | 8 | 24% |
| Unknown | 12 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2015.
All research outputs
#13,214,896
of 22,829,683 outputs
Outputs from Biological Trace Element Research
#918
of 2,025 outputs
Outputs of similar age
#125,823
of 274,379 outputs
Outputs of similar age from Biological Trace Element Research
#9
of 28 outputs
Altmetric has tracked 22,829,683 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,025 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,379 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.