Title |
Asymptomatic and Submicroscopic Carriage of Plasmodium knowlesi Malaria in Household and Community Members of Clinical Cases in Sabah, Malaysia
|
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Published in |
Journal of Infectious Diseases, October 2015
|
DOI | 10.1093/infdis/jiv475 |
Pubmed ID | |
Authors |
Kimberly M. Fornace, Nor Afizah Nuin, Martha Betson, Matthew J. Grigg, Timothy William, Nicholas M. Anstey, Tsin W. Yeo, Jonathan Cox, Lau Tiek Ying, Chris J. Drakeley |
Abstract |
Although asymptomatic carriage of human malaria species has been widely reported, the extent of asymptomatic, submicroscopic parasitemia for Plasmodium knowlesi is unknown. This study sampled individuals residing in households or villages of symptomatic malaria cases with the aim of detecting submicroscopic P. knowlesi in this population. Four published molecular assays were used to confirm the presence of P. knowlesi. Using latent class analysis the estimated proportion of asymptomatic individuals was 6.9% (5.6 -8.4%). This study confirms the presence of a substantial number of asymptomatic mono-infections across all age groups; further work is needed to estimate prevalence in the wider community. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 91 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 16% |
Researcher | 12 | 13% |
Student > Bachelor | 11 | 12% |
Student > Ph. D. Student | 9 | 10% |
Lecturer | 8 | 9% |
Other | 16 | 18% |
Unknown | 20 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 29% |
Agricultural and Biological Sciences | 13 | 14% |
Biochemistry, Genetics and Molecular Biology | 10 | 11% |
Immunology and Microbiology | 6 | 7% |
Business, Management and Accounting | 2 | 2% |
Other | 10 | 11% |
Unknown | 24 | 26% |