Title |
Streptococcal toxins: role in pathogenesis and disease
|
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Published in |
Cellular Microbiology, November 2015
|
DOI | 10.1111/cmi.12531 |
Pubmed ID | |
Authors |
Timothy C Barnett, Jason N Cole, Tania Rivera-Hernandez, Anna Henningham, James C Paton, Victor Nizet, Mark J Walker |
Abstract |
Group A Streptococcus (Streptococcus pyogenes; GAS), group B Streptococcus (Streptococcus agalactiae; GBS) and Streptococcus pneumoniae (pneumococcus) are host-adapted bacterial pathogens among the leading infectious causes of human morbidity and mortality. These microbes and related members of the genus Streptococcus produce an array of toxins that act against human cells or tissues, resulting in impaired immune responses and subversion of host physiological processes to benefit the invading microorganism. This toxin repertoire includes hemolysins, proteases, superantigens and other agents that ultimately enhance colonization and survival within the host and promote dissemination of the pathogen. This article is protected by copyright. All rights reserved. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Canada | 1 | <1% |
Unknown | 253 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 50 | 20% |
Student > Master | 30 | 12% |
Student > Ph. D. Student | 26 | 10% |
Researcher | 18 | 7% |
Student > Postgraduate | 14 | 5% |
Other | 32 | 13% |
Unknown | 85 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 51 | 20% |
Agricultural and Biological Sciences | 32 | 13% |
Immunology and Microbiology | 31 | 12% |
Medicine and Dentistry | 23 | 9% |
Veterinary Science and Veterinary Medicine | 6 | 2% |
Other | 25 | 10% |
Unknown | 87 | 34% |