| Title |
Complications and Postoperative Mortality Rate After Surgery for Pathological Femur Fracture Related to Bone Metastasis: Analysis of a Nationwide Database
|
|---|---|
| Published in |
Annals of Surgical Oncology, October 2015
|
| DOI | 10.1245/s10434-015-4881-9 |
| Pubmed ID | |
| Authors |
Yusuke Tsuda, Hideo Yasunaga, Hiromasa Horiguchi, Kiyohide Fushimi, Hirotaka Kawano, Sakae Tanaka |
| Abstract |
Currently, there are few reports regarding predictors of postoperative complications and short-term mortality after surgery for pathological femur fracture related to bone metastasis. Using data from the Japanese Diagnosis Procedure Combination Database from 2007 to 2012, we retrospectively identified 1497 patients who underwent internal fixation (n = 1073) or proximal femur resection and endoprosthetic reconstruction of the proximal femur (n = 424) for pathological femur fracture related to bone metastasis. Multivariable logistic regression analysis was performed to examine the relationship of various factors with postoperative complications and 30-day mortality. The overall 30-day mortality after surgery was 2.6 %, and the proportion of postoperative complications was 12.1 %. Multivariable logistic regression analysis showed that postoperative complications overall were significantly associated with older age [odds ratio (OR), 2.15; 95 % confidence interval (CI) 1.23-3.74 for age ≥80 vs. ≤59 years]; lung carcinoma (OR 2.05; 95 % CI 1.47-2.86); esophageal carcinoma (OR 4.41; 95 % CI 1.57-12.43); higher Charlson Comorbidity Index (OR 1.50; 95 % CI 1.03-2.18 for ≥9 vs. 8); and blood transfusion (OR 1.57; 95 % CI 1.14-2.15). Thirty-day mortality also was significantly higher in patients with rapid-growth tumors, visceral metastasis, internal fixation, and no postoperative chemotherapy in the univariate analysis. Older age, type of primary tumor, higher Charlson Comorbidity Index, and blood transfusion were associated with higher morbidity. These findings can provide important information to assess perioperative risk in patients with pathological femur fracture related to bone metastasis. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 65 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 15% |
| Other | 7 | 11% |
| Student > Ph. D. Student | 7 | 11% |
| Student > Bachelor | 6 | 9% |
| Researcher | 6 | 9% |
| Other | 11 | 17% |
| Unknown | 18 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 43% |
| Engineering | 4 | 6% |
| Unspecified | 2 | 3% |
| Neuroscience | 2 | 3% |
| Immunology and Microbiology | 1 | 2% |
| Other | 6 | 9% |
| Unknown | 22 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2015.
All research outputs
#17,774,664
of 22,829,683 outputs
Outputs from Annals of Surgical Oncology
#4,845
of 6,471 outputs
Outputs of similar age
#186,979
of 277,499 outputs
Outputs of similar age from Annals of Surgical Oncology
#58
of 95 outputs
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