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Increasing feasibility and utility of 18F-FDOPA PET for the management of glioma

Overview of attention for article published in Nuclear Medicine & Biology, June 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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1 policy source
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2 X users

Citations

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41 Dimensions

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68 Mendeley
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Title
Increasing feasibility and utility of 18F-FDOPA PET for the management of glioma
Published in
Nuclear Medicine & Biology, June 2015
DOI 10.1016/j.nucmedbio.2015.06.001
Pubmed ID
Authors

Christopher Bell, Nicholas Dowson, Simon Puttick, Yaniv Gal, Paul Thomas, Mike Fay, Jye Smith, Stephen Rose

Abstract

Despite radical treatment therapies, glioma continues to carry with it a uniformly poor prognosis. Patients diagnosed with WHO Grade IV glioma (glioblastomas; GBM) generally succumb within two years, even those with WHO Grade III anaplastic gliomas and WHO Grade II gliomas carry prognoses of 2-5 and 2years, respectively. PET imaging with (18)F-FDOPA allows in vivo assessment of the metabolism of glioma relative to surrounding tissues. The high sensitivity of (18)F-DOPA imaging grants utility for a number of clinical applications. A collection of published work about (18)F-FDOPA PET was made and a critical review was discussed and written. A number of research papers have been published demonstrating that in conjunction with MRI, (18)F-FDOPA PET provides greater sensitivity and specificity than these modalities in detection, grading, prognosis and validation of treatment success in both primary and recurrent gliomas. In further comparisons with (11)C-MET, (18)F-FLT, (18)F-FET and MRI, (18)F-FDOPA has shown similar or better efficacy. Recently synthesis cassettes have become available, making (18)F-FDOPA more accessible. According to the available data, (18)F-FDOPA PET is a viable radiotracer for imaging and treatment planning of gliomas. ADVANCES IN KNOWLEDGE AND IMPLICATION FOR PATIENT CARE: (18)F-FDOPA PET appears to be a viable radiopharmaceutical for the diagnosis and treatment planning of gliomas cases, improving on that of MRI and (18)F-FDG PET.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 68 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 16%
Researcher 9 13%
Student > Doctoral Student 7 10%
Student > Master 6 9%
Other 6 9%
Other 13 19%
Unknown 16 24%
Readers by discipline Count As %
Medicine and Dentistry 28 41%
Chemistry 6 9%
Neuroscience 3 4%
Engineering 3 4%
Agricultural and Biological Sciences 2 3%
Other 10 15%
Unknown 16 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2018.
All research outputs
#7,777,586
of 25,371,288 outputs
Outputs from Nuclear Medicine & Biology
#436
of 1,555 outputs
Outputs of similar age
#85,178
of 280,054 outputs
Outputs of similar age from Nuclear Medicine & Biology
#6
of 17 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,555 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,054 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.