| Title |
Galectin-3 as a novel biomarker in women with PCOS
|
|---|---|
| Published in |
Archives of Gynecology and Obstetrics, August 2018
|
| DOI | 10.1007/s00404-018-4862-x |
| Pubmed ID | |
| Authors |
Gokce Anik Ilhan, Cansu Kanlioglu, Gaye Arslan, Begum Yildizhan, Tanju Pekin |
| Abstract |
This study aimed at evaluating galectin-3 levels as a novel metabolic biomarker in women with PCOS. Ninety consecutive women with PCOS fulfilling the inclusion criteria were divided into two groups according to the presence of metabolic syndrome as MetS+ and MetS-. Clinical, hormonal, and metabolic parameters and galectin-3 levels were compared between the groups. Correlation analyses were performed between galectin-3 and clinical and metabolic parameters. Ninety PCOS subjects were enrolled in the study, 25 of which were diagnosed with MetS. Waist-to-hip ratio, systolic and diastolic blood pressures, triglyceride, HOMA-IR, FAI, FGS, and galectin-3 levels were significantly higher in the MetS+ group compared with the MetS- group (13.19 ± 5.63 vs 9.37 ± 3.99 ng/mL, respectively, p = 0.001). HDL cholesterol was significantly higher in the MetS- group than in the MetS+ one. Galectin-3 levels were found to be positively correlated with systolic blood pressure (r = 0.450, p < 0.01), diastolic blood pressure (r = 0.293, p < 0.01), and triglyceride levels (r = 0.218, p < 0.05) in women with PCOS. Galectin-3 may be a promising novel biomarker in women with PCOS. Galectin-3 levels were significantly higher in the MetS+ group compared with the MetS- one and positively correlated with systolic, diastolic blood pressures and triglyceride levels in women with PCOS. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 23 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 22% |
| Student > Master | 3 | 13% |
| Student > Doctoral Student | 2 | 9% |
| Student > Ph. D. Student | 2 | 9% |
| Other | 2 | 9% |
| Other | 0 | 0% |
| Unknown | 9 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 26% |
| Medicine and Dentistry | 6 | 26% |
| Agricultural and Biological Sciences | 1 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
| Unknown | 9 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2018.
All research outputs
#18,550,468
of 23,815,455 outputs
Outputs from Archives of Gynecology and Obstetrics
#1,215
of 2,066 outputs
Outputs of similar age
#240,368
of 332,291 outputs
Outputs of similar age from Archives of Gynecology and Obstetrics
#16
of 27 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,066 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.