| Title |
Microbiological profile and susceptibility pattern of surgical site infections related to orthopaedic trauma
|
|---|---|
| Published in |
International Orthopaedics, August 2018
|
| DOI | 10.1007/s00264-018-4076-7 |
| Pubmed ID | |
| Authors |
Felipe Francisco Tuon, Juliette Cieslinski, Ana Flávia Miyazaki Ono, Fernanda Lie Goto, Julia Maria Machinski, Letícia Kist Mantovani, Liliana Ramirez Kosop, Maisa Sayuri Namba, Jaime Luis Rocha |
| Abstract |
Understanding the epidemiology of microorganisms associated with surgical site infections related to orthopaedic trauma (SSI-ROT) is important in establishing treatment protocols. The aim of this study was to evaluate the etiology and susceptibility pattern of SSIs related to orthopaedic trauma in a Brazilian reference hospital for trauma. Patients with SSI-ROT in a Brazilian reference hospital for trauma were retrospectively analyzed. All patients with orthopaedic trauma who underwent a surgical procedure and developed SSI within one year were included. All patients had culture samples from the surgical site obtained from biopsy of bone or soft tissue. Clinical and epidemiological data of the patients were collected. A total of 147 patients with trauma-related infection were included in the analysis. The mean time to infection was 55.5 days, and the mean duration of hospitalization was 20.0 days. The in-hospital mortality rate after infection was 5.4%. Cultures were obtained from all patients, with 104 samples obtained from soft tissues and 43 samples from bone. The positivity rate was 93.2%. Among the isolates, 56.5% (77 patients) were gram-negative bacteria and 43.8% (60 patients) were gram-positive bacteria. Staphylococcus aureus was identified in 34%, Enterobacter spp. in 14.9%, and Pseudomonas aeruginosa in 11.6%. Staphylococcus aureus presented a higher positivity in bone samples (odds ratio, 1.29; 95% CI, 1.01-1.70; p = 0.04). Few microorganisms were multi-resistant. SSI in orthopaedic trauma can be associated with gram-negative bacilli, the susceptibility profile of which suggested that most infections occur after discharge. Staphylococcus aureus infections were commonly caused by methicillin-susceptible isolates, and this susceptibility to oral antibiotic options helps in the dehospitalization of patients. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 15% |
| Student > Master | 6 | 15% |
| Student > Doctoral Student | 4 | 10% |
| Other | 3 | 7% |
| Researcher | 3 | 7% |
| Other | 5 | 12% |
| Unknown | 14 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 27% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Engineering | 2 | 5% |
| Immunology and Microbiology | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 18 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2018.
All research outputs
#20,529,173
of 23,098,660 outputs
Outputs from International Orthopaedics
#1,281
of 1,459 outputs
Outputs of similar age
#288,972
of 331,122 outputs
Outputs of similar age from International Orthopaedics
#23
of 27 outputs
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