Title |
Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa
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Published in |
AIDS and Behavior, August 2018
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DOI | 10.1007/s10461-018-2232-0 |
Pubmed ID | |
Authors |
Hyunsuk Yoo, Juyeon Lee, Jae-Joon Yim, Till Bärnighausen, Frank Tanser, Sue K. Park |
Abstract |
We investigated whether mortality risk increases with the number of full-term pregnancies in HIV-infected women. Our study is based on data from the ACDIS cohort, collected in rural KwaZulu-Natal, South Africa. Mortality risk for different number of pregnancies in HIV-infected women was analyzed using Cox proportional hazards model. The risk of TB or AIDS mortality in HIV-uninfected women did not change with the number of full-term pregnancies, while the corresponding risk increased markedly in HIV-infected women. The risk of TB or AIDS mortality increased 1.48-fold (95% CI 1.25-1.75), 1.76-fold (95% CI 1.45-2.13), and 1.59-fold (95% CI 1.31-1.94) for one, two, and three or more full-term pregnancies compared to none, respectively. Finally, women who are young (age < 26) have greater risk of TB or AIDS mortality compared to women who are old (age ≥ 26), and women residing in rural areas have greater risk compared to women who reside in non-rural areas. |
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United States | 2 | 50% |
Venezuela, Bolivarian Republic of | 1 | 25% |
United Kingdom | 1 | 25% |
Demographic breakdown
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 10 | 19% |
Researcher | 7 | 13% |
Student > Bachelor | 4 | 8% |
Unspecified | 4 | 8% |
Lecturer | 2 | 4% |
Other | 7 | 13% |
Unknown | 18 | 35% |
Readers by discipline | Count | As % |
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Nursing and Health Professions | 5 | 10% |
Unspecified | 4 | 8% |
Social Sciences | 3 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 6 | 12% |
Unknown | 17 | 33% |