Title |
Nanoparticles for nucleic-acid-based biosensing: opportunities, challenges, and prospects
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Published in |
Analytical & Bioanalytical Chemistry, August 2018
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DOI | 10.1007/s00216-018-1273-6 |
Pubmed ID | |
Authors |
Susana Campuzano, Paloma Yáñez-Sedeño, José M. Pingarrón |
Abstract |
Electrochemical nucleic-acid-based biosensing strategies involving the use of nanoparticles as electrode modifiers and as advanced labels are attractive options for the determination of substances that are relevant clinically, from an environmental perspective, and to food analysis, as these strategies are able to overcome some of the well-known limitations of conventional methodologies for routine applications. In this article, we provide a selective overview of current strategies for nucleic acid electrochemical biosensing based on nanoparticles, in order to demonstrate the relevance and potential of these strategies to readers familiar with this field and to non-experts. The benefits provided by the use of nanoparticles, including enhanced analytical performance of the resulting electrochemical biosensors, as well as the main challenges to be solved and potential future advances in this field are discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Belgium | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 9 | 22% |
Researcher | 9 | 22% |
Student > Bachelor | 4 | 10% |
Student > Doctoral Student | 2 | 5% |
Lecturer | 1 | 2% |
Other | 5 | 12% |
Unknown | 11 | 27% |
Readers by discipline | Count | As % |
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Chemistry | 6 | 15% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Agricultural and Biological Sciences | 4 | 10% |
Engineering | 4 | 10% |
Chemical Engineering | 2 | 5% |
Other | 5 | 12% |
Unknown | 15 | 37% |