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Changes in pulmonary function after definitive radiotherapy for NSCLC

Overview of attention for article published in Radiotherapy & Oncology, October 2015
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Title
Changes in pulmonary function after definitive radiotherapy for NSCLC
Published in
Radiotherapy & Oncology, October 2015
DOI 10.1016/j.radonc.2015.09.029
Pubmed ID
Authors

Tine Schytte, Søren M Bentzen, Carsten Brink, Olfred Hansen

Abstract

The objective of this study was to identify factors associated with early and long-term pulmonary function (PF) changes after definitive radiotherapy for NSCLC patients. PF was measured by spirometry i.e. forced expiratory volume in 1s (FEV1), and forced vital capacity (FVC). Early (within the first year) PF change was analyzed in 211 patients with 986 pairs of PF-tests (PFTs). Long-term PF change was analyzed relative to the PF at 12months after radiotherapy in 106 patients (1286 PFTs). To investigate the impact of patient and treatment related factors on PF, they were tested as covariates in multivariable analysis. Early PF change was quantified at six months after the start of radiotherapy. Smoking status and increasing V60 was associated with a significant decrease in PF, whereas smoking was protective. In addition, neoadjuvant chemotherapy had a negative impact on FVC. Long-term FEV1 and FVC were analyzed using linear regression. Treatment year and V60 had a significant impact on loss of FEV1. V60 had a significant impact on FVC changes. In this study, early PF change reached a plateau at 6months after the start of radiotherapy for NSCLC. Large volume of lung receiving high dose was associated with long-term FEV1 change.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 29%
Researcher 7 25%
Other 4 14%
Student > Postgraduate 2 7%
Student > Bachelor 1 4%
Other 3 11%
Unknown 3 11%
Readers by discipline Count As %
Medicine and Dentistry 16 57%
Engineering 2 7%
Nursing and Health Professions 1 4%
Physics and Astronomy 1 4%
Agricultural and Biological Sciences 1 4%
Other 2 7%
Unknown 5 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2015.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Radiotherapy & Oncology
#3,668
of 4,846 outputs
Outputs of similar age
#212,532
of 290,039 outputs
Outputs of similar age from Radiotherapy & Oncology
#44
of 94 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,846 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,039 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 94 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.