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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy
|
|---|---|
| Published in |
Nature Reviews Clinical Oncology, August 2018
|
| DOI | 10.1038/s41571-018-0075-2 |
| Pubmed ID | |
| Authors |
Kris M. Mahadeo, Sajad J. Khazal, Hisham Abdel-Azim, Julie C. Fitzgerald, Agne Taraseviciute, Catherine M. Bollard, Priti Tewari, Christine Duncan, Chani Traube, David McCall, Marie E. Steiner, Ira M. Cheifetz, Leslie E. Lehmann, Rodrigo Mejia, John M. Slopis, Rajinder Bajwa, Partow Kebriaei, Paul L. Martin, Jerelyn Moffet, Jennifer McArthur, Demetrios Petropoulos, Joan O’Hanlon Curry, Sarah Featherston, Jessica Foglesong, Basirat Shoberu, Alison Gulbis, Maria E. Mireles, Lisa Hafemeister, Cathy Nguyen, Neena Kapoor, Katayoun Rezvani, Sattva S. Neelapu, Elizabeth J. Shpall |
| Abstract |
In 2017, an autologous chimeric antigen receptor (CAR) T cell therapy indicated for children and young adults with relapsed and/or refractory CD19+ acute lymphoblastic leukaemia became the first gene therapy to be approved in the USA. This innovative form of cellular immunotherapy has been associated with remarkable response rates but is also associated with unique and often severe toxicities, which can lead to rapid cardiorespiratory and/or neurological deterioration. Multidisciplinary medical vigilance and the requisite health-care infrastructure are imperative to ensuring optimal patient outcomes, especially as these therapies transition from research protocols to standard care. Herein, authors representing the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Hematopoietic Stem Cell Transplantation (HSCT) Subgroup and the MD Anderson Cancer Center CAR T Cell Therapy-Associated Toxicity (CARTOX) Program have collaborated to provide comprehensive consensus guidelines on the care of children receiving CAR T cell therapy. |
X Demographics
The data shown below were collected from the profiles of 85 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 20 | 24% |
| United Kingdom | 4 | 5% |
| France | 4 | 5% |
| Germany | 3 | 4% |
| India | 3 | 4% |
| Greece | 2 | 2% |
| Kenya | 2 | 2% |
| Switzerland | 2 | 2% |
| Australia | 2 | 2% |
| Other | 12 | 14% |
| Unknown | 31 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 61 | 72% |
| Practitioners (doctors, other healthcare professionals) | 11 | 13% |
| Scientists | 7 | 8% |
| Science communicators (journalists, bloggers, editors) | 6 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 292 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 292 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 43 | 15% |
| Researcher | 41 | 14% |
| Student > Ph. D. Student | 26 | 9% |
| Student > Doctoral Student | 22 | 8% |
| Student > Master | 19 | 7% |
| Other | 47 | 16% |
| Unknown | 94 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 94 | 32% |
| Biochemistry, Genetics and Molecular Biology | 25 | 9% |
| Immunology and Microbiology | 17 | 6% |
| Agricultural and Biological Sciences | 13 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 4% |
| Other | 30 | 10% |
| Unknown | 100 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 116. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2024.
All research outputs
#369,966
of 25,774,185 outputs
Outputs from Nature Reviews Clinical Oncology
#70
of 2,361 outputs
Outputs of similar age
#7,791
of 341,771 outputs
Outputs of similar age from Nature Reviews Clinical Oncology
#4
of 39 outputs
Altmetric has tracked 25,774,185 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,361 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.1. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,771 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.