| Title |
A multicenter study investigating the molecular fingerprint of psychological resilience in breast cancer patients: study protocol of the SCAN-B resilience study
|
|---|---|
| Published in |
BMC Cancer, August 2018
|
| DOI | 10.1186/s12885-018-4669-y |
| Pubmed ID | |
| Authors |
Ulrika Axelsson, Lisa Rydén, Per Johnsson, Patrik Edén, Johanna Månsson, Ingalill Rahm Hallberg, Carl A. K. Borrebaeck |
| Abstract |
Individual patients differ in their psychological response when receiving a cancer diagnosis, in this case breast cancer. Given the same disease burden, some patients master the situation well, while others experience a great deal of stress, depression and lowered quality of life. Patients with high psychological resilience are likely to experience fewer stress reactions and better adapt to and manage the life threat and the demanding treatment that follows the diagnosis. If this phenomenon of mastering difficult situations is reflected also in biomolecular processes is not much studied, nor has its capacity for impacting the cancer prognosis been addressed. This project specifically aims, for the first time, to investigate how a breast cancer patient's psychological resilience is coupled to biomolecular parameters using advanced "omics" and, as a secondary aim, whether it relates to prognosis and quality of life one year after diagnosis. The study population consists of newly diagnosed breast cancer patients enrolled in the Sweden Cancerome Analysis Network - Breast (SCAN-B) at four hospitals in Sweden. At the time of cancer diagnosis, the patient fills out the standardized method to measure psychological resilience, the "Connor-Davidson Resilience scale" (CD-RISC), the quality of life measure SF-36, as well as providing social and socioeconomic variables. In addition, one blood sample is collected. At the one-year follow-up, the patient will be subjected to the same assessments, and we also collect information regarding smoking, exercise habits, and BMI, as well as patients' trust in the treatment and their satisfaction with the care and treatment. This explorative hypothesis-generating project will pave the way for larger validation studies, potentially leading to a standardized method of measuring psychological resilience as an important parameter in cancer care. Revealing the body-mind interaction, in terms of psychological resilience and quality of life, will herald the development of truly personalized psychosocial care and cancer intervention treatment strategies. This is a retrospectively registered trial at ClinicalTrials.gov, ID: NCT03430492 on February 6, 2018. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 98 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 11% |
| Student > Bachelor | 11 | 11% |
| Student > Ph. D. Student | 8 | 8% |
| Student > Postgraduate | 7 | 7% |
| Researcher | 5 | 5% |
| Other | 13 | 13% |
| Unknown | 43 | 44% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 15% |
| Nursing and Health Professions | 11 | 11% |
| Psychology | 11 | 11% |
| Sports and Recreations | 3 | 3% |
| Social Sciences | 3 | 3% |
| Other | 12 | 12% |
| Unknown | 43 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2018.
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#20,529,980
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Outputs from BMC Cancer
#6,550
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Outputs of similar age
#288,630
of 330,726 outputs
Outputs of similar age from BMC Cancer
#106
of 138 outputs
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