| Title |
Prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in community dwelling postmenopausal Hungarian women
|
|---|---|
| Published in |
Osteoporosis International, December 2003
|
| DOI | 10.1007/s00198-003-1566-1 |
| Pubmed ID | |
| Authors |
H. P. Bhattoa, P. Bettembuk, S. Ganacharya, A. Balogh |
| Abstract |
Hypovitaminosis D can result in low bone mass. The prevalence of hypovitaminosis D has public health implications, especially where data are lacking. Since diet and sunlight are the two souces of vitamin D, the results obtained in one geographical region may not be universally applicable. The aim of this study is to characterize the prevalence and seasonal variation of hypovitaminosis D and its relationship to bone metabolism in community dwelling postmenopausal Hungarian women. We determined serum levels of 25-hydroxyvitamin D (25-OH-D), PTH, osteocalcin (OC), degradation products of C-terminal telopeptides of type-I collagen (CTx), dietary calcium intake and BMD at L2-L4 lumbar spine (LS) and femur neck (FN) in 319 randomly selected ambulatory postmenopausal women. The prevalence of hypovitaminosis D (serum 25-OH-D< or =50 nmol/l) was 56.7%. On comparing patients with normal and low 25-OH-D, a significant difference was found in age (61.6+/-8.5 years versus 67.3+/-9.9 years; P<0.001), PTH (3.9+/-1.9 pmol/l versus 4.3+/-2.7 pmol/l; P<0.05), FN BMD (0.802+/-0.123 g/cm(2) versus 0.744+/-0.125 g/cm(2); P<0.001) and dietary calcium intake (714.4+/-199.4 g/day versus 607.9+/-233 g/day; P<0.001). Osteoporotic patients had a significantly lower 25-OH-D (37.6+/-19.8 nmol/l versus 56.4+/-24 nmol/l; P<0.001) and dietary calcium intake (519.2+/-244.5 mg/day versus 718.2+/-164.3 mg/day; P<0.001). After controlling for all other variables, 25-OH-D was found to be significantly associated with age, the average hours of sunshine in the 3 months prior to 25-OH-D level determination and dietary calcium intake ( r(2)=0.190; P<0.001). For FN BMD, significant independent predictors were age, body mass index, 25-OH-D and dietary calcium intake ( r(2)=0.435; P<0.001). The prevalence of hypovitaminosis D during spring, summer, autumn and winter was 71%, 46.3%, 49.4% and 56.7%, respectively. There was significant seasonal variation in 25-OH-D, PTH, OC, calcium intake and FN BMD. There is a high prevalence of hypovitaminosis D in healthy postmenopausal Hungarian women, and FN BMD is associated with serum 25-OH-D and dietary calcium intake. |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 2% |
| Unknown | 44 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 16% |
| Student > Master | 6 | 13% |
| Other | 5 | 11% |
| Student > Bachelor | 3 | 7% |
| Professor > Associate Professor | 3 | 7% |
| Other | 9 | 20% |
| Unknown | 12 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 38% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Nursing and Health Professions | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Mathematics | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 16 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2015.
All research outputs
#4,180,468
of 22,830,751 outputs
Outputs from Osteoporosis International
#673
of 3,610 outputs
Outputs of similar age
#13,533
of 133,256 outputs
Outputs of similar age from Osteoporosis International
#2
of 11 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,610 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 80% of its peers.
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We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.