| Title |
Allogeneic stem cell transplantation recipients requiring intensive care: time is of the essence
|
|---|---|
| Published in |
Annals of Hematology, May 2018
|
| DOI | 10.1007/s00277-018-3320-y |
| Pubmed ID | |
| Authors |
Corentin Orvain, Francois Beloncle, Jean-Francois Hamel, Aurélien Sutra Del Galy, Sylvain Thépot, Mélanie Mercier, Achille Kouatchet, Jonathan Farhi, Sylvie Francois, Norbert Ifrah, Alain Mercat, Pierre Asfar, Mathilde Hunault-Berger, Aline Tanguy-Schmidt |
| Abstract |
The benefit of early admission of allogeneic stem cell transplantation (SCT) recipients to the intensive care unit (ICU) as soon as they develop organ injury is unknown. We performed a retrospective study on 92 patients admitted to the ICU to determine the impact of time from organ injury to ICU admission on outcome. The number of organ injuries prior to ICU admission was associated with an increased in-hospital mortality (OR 1.7, 95% CI 1-2.7, p = 0.04). Time between first organ injury and ICU admission was also associated with an increased in-hospital survival (OR 1.4, 95% CI 1.1-1.8, p = 0.02). A score combining these two covariates-the number of organ injuries/day (sum of days spent with each individual organ injury)-further improved the prediction of hospital survival. Patients with more organ injuries/day had significantly higher in-hospital mortality rate even after adjustment for refractory acute GVHD and the SOFA (OR 1.3, 95% CI 1-1.7, p = 0.02). Early ICU admission of allogeneic SCT recipients to the ICU as soon as they develop organ injury is associated with decreased in-hospital mortality. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 22% |
| Other | 6 | 19% |
| Student > Doctoral Student | 1 | 3% |
| Student > Bachelor | 1 | 3% |
| Professor > Associate Professor | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 16 | 50% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 10 | 31% |
| Engineering | 3 | 9% |
| Social Sciences | 1 | 3% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Neuroscience | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 15 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2018.
All research outputs
#18,646,262
of 23,099,576 outputs
Outputs from Annals of Hematology
#1,487
of 2,206 outputs
Outputs of similar age
#253,127
of 326,415 outputs
Outputs of similar age from Annals of Hematology
#27
of 47 outputs
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