You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Bench to bedside: NK cells and control of metastasis
|
|---|---|
| Published in |
Clinical Immunology, October 2015
|
| DOI | 10.1016/j.clim.2015.10.001 |
| Pubmed ID | |
| Authors |
Yelena Krasnova, Eva Maria Putz, Mark J. Smyth, Fernando Souza-Fonseca-Guimaraes |
| Abstract |
Natural killer (NK) cells play a critical role in host immune responses against tumor growth and metastasis. The numerous mechanisms used by NK cells to regulate and control cancer metastasis include interactions with tumor cells via specific receptors and ligands as well as direct cytotoxicity and cytokine-induced effector mechanisms. NK cells also play a role in tumor immunosurveillance and inhibition of metastases formation by recognition and killing of tumor cells. In this review, we provide an overview of the molecular mechanisms of NK cell responses against tumor metastases and discuss multiple strategies by which tumors evade NK cell-mediated surveillance. With an increasing understanding of the molecular mechanisms driving NK cell activity, there is a growing potential for the development of new cancer immunotherapies. Here we provide a historical background on NK cell-based therapies and discuss the implications of recent and ongoing clinical trials using novel NK cell-based immunotherapy. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| Unknown | 6 | 86% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Austria | 1 | <1% |
| South Africa | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 103 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 19% |
| Researcher | 19 | 18% |
| Student > Bachelor | 18 | 17% |
| Student > Master | 16 | 15% |
| Student > Doctoral Student | 7 | 7% |
| Other | 9 | 8% |
| Unknown | 18 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 26 | 24% |
| Agricultural and Biological Sciences | 24 | 22% |
| Medicine and Dentistry | 14 | 13% |
| Biochemistry, Genetics and Molecular Biology | 12 | 11% |
| Computer Science | 2 | 2% |
| Other | 12 | 11% |
| Unknown | 17 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2023.
All research outputs
#2,231,696
of 25,374,647 outputs
Outputs from Clinical Immunology
#121
of 2,829 outputs
Outputs of similar age
#31,351
of 294,828 outputs
Outputs of similar age from Clinical Immunology
#1
of 25 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,829 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 294,828 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.