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Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Overview of attention for article published in Nature Genetics, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
20 news outlets
blogs
3 blogs
twitter
54 X users
googleplus
3 Google+ users

Citations

dimensions_citation
519 Dimensions

Readers on

mendeley
535 Mendeley
citeulike
1 CiteULike
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Title
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Published in
Nature Genetics, October 2015
DOI 10.1038/ng.3424
Pubmed ID
Abstract

Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, complex skin disease, we performed a meta-analysis of >15 million genetic variants in 21,399 cases and 95,464 controls from populations of European, African, Japanese and Latino ancestry, followed by replication in 32,059 cases and 228,628 controls from 18 studies. We identified ten new risk loci, bringing the total number of known atopic dermatitis risk loci to 31 (with new secondary signals at four of these loci). Notably, the new loci include candidate genes with roles in the regulation of innate host defenses and T cell function, underscoring the important contribution of (auto)immune mechanisms to atopic dermatitis pathogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 54 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 535 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Sweden 1 <1%
Unknown 532 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 97 18%
Student > Ph. D. Student 87 16%
Student > Bachelor 49 9%
Student > Master 42 8%
Other 34 6%
Other 90 17%
Unknown 136 25%
Readers by discipline Count As %
Medicine and Dentistry 102 19%
Biochemistry, Genetics and Molecular Biology 95 18%
Agricultural and Biological Sciences 63 12%
Immunology and Microbiology 25 5%
Engineering 14 3%
Other 75 14%
Unknown 161 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 205. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2018.
All research outputs
#194,440
of 25,837,817 outputs
Outputs from Nature Genetics
#301
of 7,639 outputs
Outputs of similar age
#2,577
of 297,151 outputs
Outputs of similar age from Nature Genetics
#4
of 64 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,639 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,151 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.