| Title |
Circadian Clocks as Modulators of Metabolic Comorbidity in Psychiatric Disorders
|
|---|---|
| Published in |
Current Psychiatry Reports, October 2015
|
| DOI | 10.1007/s11920-015-0637-2 |
| Pubmed ID | |
| Authors |
Rita Barandas, Dominic Landgraf, Michael J. McCarthy, David K. Welsh |
| Abstract |
Psychiatric disorders such as schizophrenia, bipolar disorder, and major depressive disorder are often accompanied by metabolic dysfunction symptoms, including obesity and diabetes. Since the circadian system controls important brain systems that regulate affective, cognitive, and metabolic functions, and neuropsychiatric and metabolic diseases are often correlated with disturbances of circadian rhythms, we hypothesize that dysregulation of circadian clocks plays a central role in metabolic comorbidity in psychiatric disorders. In this review paper, we highlight the role of circadian clocks in glucocorticoid, dopamine, and orexin/melanin-concentrating hormone systems and describe how a dysfunction of these clocks may contribute to the simultaneous development of psychiatric and metabolic symptoms. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 24% |
| Argentina | 2 | 12% |
| Spain | 1 | 6% |
| United Kingdom | 1 | 6% |
| Unknown | 9 | 53% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 12 | 71% |
| Scientists | 3 | 18% |
| Practitioners (doctors, other healthcare professionals) | 2 | 12% |
Mendeley readers
The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Chile | 1 | <1% |
| Turkey | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 122 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 14% |
| Researcher | 17 | 13% |
| Student > Master | 17 | 13% |
| Student > Bachelor | 13 | 10% |
| Student > Doctoral Student | 8 | 6% |
| Other | 29 | 23% |
| Unknown | 24 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 23% |
| Psychology | 15 | 12% |
| Agricultural and Biological Sciences | 12 | 10% |
| Neuroscience | 12 | 10% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Other | 15 | 12% |
| Unknown | 35 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2023.
All research outputs
#3,388,393
of 24,679,965 outputs
Outputs from Current Psychiatry Reports
#385
of 1,254 outputs
Outputs of similar age
#46,153
of 288,848 outputs
Outputs of similar age from Current Psychiatry Reports
#7
of 13 outputs
Altmetric has tracked 24,679,965 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,254 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.3. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,848 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.