Title |
The Role of Diet in Multiple Sclerosis: Mechanistic Connections and Current Evidence
|
---|---|
Published in |
Current Nutrition Reports, August 2018
|
DOI | 10.1007/s13668-018-0236-z |
Pubmed ID | |
Authors |
Ilana Katz Sand |
Abstract |
This review seeks to examine current research related to the role of diet in multiple sclerosis (MS). Recent research in preclinical models, epidemiologic studies, and limited prospectively followed cohorts provide preliminary evidence that dietary factors influence MS incidence, disease course, and symptomatology. Current evidence for the effects of fatty acids, fruits and vegetables, whole grains, dairy, and salt are reviewed. Dietary patterns including overall diet quality, caloric restriction, McDougall diet, Paleolithic diet, and Mediterranean diet are discussed. Hypotheses regarding potential mechanistic connections underlying observed effects are also presented. Several individual dietary components and patterns demonstrate potential for significant impact in MS. Definitive answers regarding the ability of diet to act as a disease modifier in MS will ultimately require large-scale clinical trials. Continued prospective studies and clinical trials to further advance this line of research are warranted. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 9 | 24% |
United Kingdom | 5 | 14% |
Spain | 4 | 11% |
Italy | 1 | 3% |
Panama | 1 | 3% |
Czechia | 1 | 3% |
Ireland | 1 | 3% |
Denmark | 1 | 3% |
Unknown | 14 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 28 | 76% |
Practitioners (doctors, other healthcare professionals) | 6 | 16% |
Scientists | 2 | 5% |
Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 276 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 37 | 13% |
Student > Master | 35 | 13% |
Student > Ph. D. Student | 21 | 8% |
Researcher | 18 | 7% |
Student > Doctoral Student | 15 | 5% |
Other | 41 | 15% |
Unknown | 109 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 43 | 16% |
Nursing and Health Professions | 33 | 12% |
Biochemistry, Genetics and Molecular Biology | 22 | 8% |
Neuroscience | 19 | 7% |
Agricultural and Biological Sciences | 10 | 4% |
Other | 26 | 9% |
Unknown | 123 | 45% |