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Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud

Overview of attention for article published in PLOS ONE, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

blogs
1 blog
twitter
50 X users

Citations

dimensions_citation
103 Dimensions

Readers on

mendeley
163 Mendeley
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5 CiteULike
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Title
Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud
Published in
PLOS ONE, October 2015
DOI 10.1371/journal.pone.0140829
Pubmed ID
Authors

Enis Afgan, Clare Sloggett, Nuwan Goonasekera, Igor Makunin, Derek Benson, Mark Crowe, Simon Gladman, Yousef Kowsar, Michael Pheasant, Ron Horst, Andrew Lonie

Abstract

Analyzing high throughput genomics data is a complex and compute intensive task, generally requiring numerous software tools and large reference data sets, tied together in successive stages of data transformation and visualisation. A computational platform enabling best practice genomics analysis ideally meets a number of requirements, including: a wide range of analysis and visualisation tools, closely linked to large user and reference data sets; workflow platform(s) enabling accessible, reproducible, portable analyses, through a flexible set of interfaces; highly available, scalable computational resources; and flexibility and versatility in the use of these resources to meet demands and expertise of a variety of users. Access to an appropriate computational platform can be a significant barrier to researchers, as establishing such a platform requires a large upfront investment in hardware, experience, and expertise. We designed and implemented the Genomics Virtual Laboratory (GVL) as a middleware layer of machine images, cloud management tools, and online services that enable researchers to build arbitrarily sized compute clusters on demand, pre-populated with fully configured bioinformatics tools, reference datasets and workflow and visualisation options. The platform is flexible in that users can conduct analyses through web-based (Galaxy, RStudio, IPython Notebook) or command-line interfaces, and add/remove compute nodes and data resources as required. Best-practice tutorials and protocols provide a path from introductory training to practice. The GVL is available on the OpenStack-based Australian Research Cloud (http://nectar.org.au) and the Amazon Web Services cloud. The principles, implementation and build process are designed to be cloud-agnostic. This paper provides a blueprint for the design and implementation of a cloud-based Genomics Virtual Laboratory. We discuss scope, design considerations and technical and logistical constraints, and explore the value added to the research community through the suite of services and resources provided by our implementation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 50 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
China 2 1%
Netherlands 1 <1%
Sweden 1 <1%
United Kingdom 1 <1%
Denmark 1 <1%
Italy 1 <1%
Spain 1 <1%
United States 1 <1%
Luxembourg 1 <1%
Other 1 <1%
Unknown 152 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 21%
Student > Ph. D. Student 26 16%
Student > Bachelor 19 12%
Student > Master 13 8%
Student > Doctoral Student 11 7%
Other 31 19%
Unknown 28 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 25%
Biochemistry, Genetics and Molecular Biology 36 22%
Computer Science 24 15%
Immunology and Microbiology 7 4%
Chemistry 4 2%
Other 23 14%
Unknown 29 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 40. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2016.
All research outputs
#1,044,823
of 25,706,302 outputs
Outputs from PLOS ONE
#13,402
of 224,010 outputs
Outputs of similar age
#15,548
of 295,964 outputs
Outputs of similar age from PLOS ONE
#310
of 5,587 outputs
Altmetric has tracked 25,706,302 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 224,010 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,964 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 5,587 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.