| Title |
Brief Report: Maternal Opioid Prescription from Preconception Through Pregnancy and the Odds of Autism Spectrum Disorder and Autism Features in Children
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, August 2018
|
| DOI | 10.1007/s10803-018-3721-8 |
| Pubmed ID | |
| Authors |
Eric Rubenstein, Jessica C. Young, Lisa A. Croen, Carolyn DiGuiseppi, Nicole F. Dowling, Li-Ching Lee, Laura Schieve, Lisa D. Wiggins, Julie Daniels |
| Abstract |
Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism features in the Study to Explore Early Development, a case-control study of neurodevelopment. Preconception opioid prescription was associated with 2.43 times the odds of ASD [95% confidence interval (CI) 0.99, 6.02] and 2.64 times the odds of ASD/DD with autism features (95% CI 1.10, 6.31) compared to mothers without prescriptions. Odds for ASD and ASD/DD were non-significantly elevated for first trimester prescriptions. Work exploring mechanisms and timing between peri-pregnancy opioid use and child neurodevelopment is needed. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 27% |
| Spain | 1 | 9% |
| United Kingdom | 1 | 9% |
| Unknown | 6 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 73% |
| Practitioners (doctors, other healthcare professionals) | 2 | 18% |
| Scientists | 1 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 100 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 12% |
| Student > Doctoral Student | 12 | 12% |
| Researcher | 10 | 10% |
| Student > Bachelor | 9 | 9% |
| Student > Master | 8 | 8% |
| Other | 12 | 12% |
| Unknown | 37 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 21% |
| Psychology | 11 | 11% |
| Social Sciences | 10 | 10% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Nursing and Health Professions | 3 | 3% |
| Other | 10 | 10% |
| Unknown | 42 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2020.
All research outputs
#2,259,898
of 25,654,806 outputs
Outputs from Journal of Autism and Developmental Disorders
#963
of 5,484 outputs
Outputs of similar age
#44,670
of 342,990 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#25
of 81 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,990 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.