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Grading keratinocyte atypia in actinic keratosis: a correlation of reflectance confocal microscopy and histopathology

Overview of attention for article published in Journal of the European Academy of Dermatology & Venereology, August 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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1 policy source
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5 X users
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1 Facebook page

Citations

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43 Dimensions

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24 Mendeley
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Title
Grading keratinocyte atypia in actinic keratosis: a correlation of reflectance confocal microscopy and histopathology
Published in
Journal of the European Academy of Dermatology & Venereology, August 2015
DOI 10.1111/jdv.13215
Pubmed ID
Authors

G. Pellacani, M. Ulrich, A. Casari, T.W. Prow, F. Cannillo, E. Benati, A. Losi, A.M. Cesinaro, C. Longo, G. Argenziano, H.P. Soyer

Abstract

Actinic Keratosis (AK) is the clinical manifestation of cutaneous dysplasia of epidermal keratinocytes, with progressive trend towards squamous cell carcinoma. To evaluate the strength of the correlation between keratinocyte atypia, as detected by Reflectance Confocal Microscopy (RCM) and histopathology, and to develop a more objective atypia grading scale for RCM quantification, through a discrete ranking. A total of 48 AKs and two control areas (photodamaged and non-photodamaged skin) were selected for this study. All these areas were documented by RCM and biopsied for histopathology. One representative image of the epidermis was selected for RCM and for histopathology and used for side-by-side comparison with purpose written software. The assessor chose which of two images displayed more keratinocyte atypia, and an ordered list from the image showing the least to the most keratinocyte atypia was generated. Three evaluations were obtained for RCM and two for histopathology. Good interobserver correlation was obtained for RCM and histopathology grading, with high concordance between RCM and histopathology grading. Expert rater scan consistently distinguish different grades of cytological atypia. Non-invasive RCM data from in vivo imaging can be graded for keratinocyte atypia, comparable to histopathological grading.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Professor 4 17%
Other 3 13%
Student > Ph. D. Student 3 13%
Researcher 3 13%
Professor > Associate Professor 2 8%
Other 3 13%
Unknown 6 25%
Readers by discipline Count As %
Medicine and Dentistry 15 63%
Agricultural and Biological Sciences 1 4%
Nursing and Health Professions 1 4%
Unknown 7 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2019.
All research outputs
#5,289,914
of 25,371,288 outputs
Outputs from Journal of the European Academy of Dermatology & Venereology
#1,141
of 5,367 outputs
Outputs of similar age
#61,421
of 276,622 outputs
Outputs of similar age from Journal of the European Academy of Dermatology & Venereology
#11
of 65 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,367 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.8. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.