Title |
T[20] repeat in the 3′-untranslated region of the MT1X gene: a marker with high sensitivity and specificity to detect microsatellite instability in colorectal cancer
|
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Published in |
International Journal of Colorectal Disease, November 2011
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DOI | 10.1007/s00384-011-1365-7 |
Pubmed ID | |
Authors |
Luca Morandi, Dario de Biase, Michela Visani, Adriana Monzoni, Annalisa Tosi, Mauro Brulatti, Daniela Turchetti, Paola Baccarini, Giovanni Tallini, Annalisa Pession |
Abstract |
Stratifying patients defective in mismatch repair (dMMR) with high microsatellite instability (MSI-H) in colorectal cancer (CRC) is of increasing relevance and may provide a more tailored approach to CRC adjuvant therapy. Here, we describe the discovery of a new MSI marker for colorectal cancer located in the 3'-untranslated region (3'UTR, T20 mononucleotide repeat) of the metallothionein 1X gene (MT1XT20). |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
South Africa | 1 | 3% |
Unknown | 31 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 34% |
Student > Master | 5 | 16% |
Student > Ph. D. Student | 4 | 13% |
Other | 1 | 3% |
Student > Doctoral Student | 1 | 3% |
Other | 0 | 0% |
Unknown | 10 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 38% |
Medicine and Dentistry | 4 | 13% |
Biochemistry, Genetics and Molecular Biology | 3 | 9% |
Computer Science | 1 | 3% |
Engineering | 1 | 3% |
Other | 0 | 0% |
Unknown | 11 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2020.
All research outputs
#4,665,630
of 22,659,164 outputs
Outputs from International Journal of Colorectal Disease
#180
of 1,826 outputs
Outputs of similar age
#39,944
of 239,459 outputs
Outputs of similar age from International Journal of Colorectal Disease
#2
of 21 outputs
Altmetric has tracked 22,659,164 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,826 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done well, scoring higher than 87% of its peers.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.