| Title |
UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, April 2008
|
| DOI | 10.1007/s00018-008-8072-8 |
| Pubmed ID | |
| Authors |
C. Schuberth, A. Buchberger |
| Abstract |
The highly conserved AAA ATPase Cdc48/p97 acts on ubiquitylated substrate proteins in cellular processes as diverse as the fusion of homotypic membranes and the degradation of misfolded proteins. The 'Ubiquitin regulatory X' (UBX) domain-containing proteins constitute the so far largest family of Cdc48/p97 cofactors. UBX proteins are involved in substrate recruitment to Cdc48/p97 and in the temporal and spatial regulation of its activity. In combination with UBX-like proteins and other cofactors, they can assemble into a large variety of Cdc48/p97-cofactor complexes possessing distinct cellular functions. This review gives an overview of the different subfamilies of UBX proteins and their functions, and discusses general principles of Cdc48/p97 regulation by these cofactors. |
Mendeley readers
The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Germany | 2 | <1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| United Kingdom | 1 | <1% |
| Japan | 1 | <1% |
| China | 1 | <1% |
| Unknown | 193 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 52 | 26% |
| Student > Bachelor | 30 | 15% |
| Researcher | 29 | 14% |
| Student > Master | 23 | 11% |
| Professor | 13 | 6% |
| Other | 31 | 15% |
| Unknown | 25 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 94 | 46% |
| Biochemistry, Genetics and Molecular Biology | 58 | 29% |
| Medicine and Dentistry | 10 | 5% |
| Neuroscience | 3 | 1% |
| Chemistry | 3 | 1% |
| Other | 8 | 4% |
| Unknown | 27 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2015.
All research outputs
#6,754,776
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#1,431
of 4,151 outputs
Outputs of similar age
#25,443
of 81,575 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#19
of 39 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 81,575 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.