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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Physiochemical drug properties associated with in vivo toxicological outcomes
|
|---|---|
| Published in |
Bioorganic & Medicinal Chemistry Letters, July 2008
|
| DOI | 10.1016/j.bmcl.2008.07.071 |
| Pubmed ID | |
| Authors |
Jason D. Hughes, Julian Blagg, David A. Price, Simon Bailey, Gary A. DeCrescenzo, Rajesh V. Devraj, Edmund Ellsworth, Yvette M. Fobian, Michael E. Gibbs, Richard W. Gilles, Nigel Greene, Enoch Huang, Teresa Krieger-Burke, Jens Loesel, Travis Wager, Larry Whiteley, Yao Zhang |
| Abstract |
Relationships between physicochemical drug properties and toxicity were inferred from a data set consisting of animal in vivo toleration (IVT) studies on 245 preclinical Pfizer compounds; an increased likelihood of toxic events was found for less polar, more lipophilic compounds. This trend held across a wide range of types of toxicity and across a broad swath of chemical space. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 14% |
| Unknown | 6 | 86% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 625 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 9 | 1% |
| United States | 5 | <1% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| Belgium | 1 | <1% |
| Denmark | 1 | <1% |
| Romania | 1 | <1% |
| Germany | 1 | <1% |
| Spain | 1 | <1% |
| Other | 3 | <1% |
| Unknown | 601 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 146 | 23% |
| Student > Ph. D. Student | 127 | 20% |
| Student > Master | 68 | 11% |
| Student > Bachelor | 45 | 7% |
| Other | 37 | 6% |
| Other | 85 | 14% |
| Unknown | 117 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 250 | 40% |
| Pharmacology, Toxicology and Pharmaceutical Science | 54 | 9% |
| Biochemistry, Genetics and Molecular Biology | 52 | 8% |
| Agricultural and Biological Sciences | 51 | 8% |
| Medicine and Dentistry | 23 | 4% |
| Other | 49 | 8% |
| Unknown | 146 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 53. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2023.
All research outputs
#802,894
of 25,374,917 outputs
Outputs from Bioorganic & Medicinal Chemistry Letters
#21
of 13,778 outputs
Outputs of similar age
#1,624
of 97,408 outputs
Outputs of similar age from Bioorganic & Medicinal Chemistry Letters
#1
of 183 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,778 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 97,408 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 183 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.