Title |
Risk factors for surgical site infection following colorectal resection: a multi-institutional study
|
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Published in |
International Journal of Colorectal Disease, October 2015
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DOI | 10.1007/s00384-015-2413-5 |
Pubmed ID | |
Authors |
Derek B. Hennessey, John P. Burke, Tara Ni-Dhonochu, Conor Shields, Desmond C. Winter, Kenneth Mealy |
Abstract |
Surgical site infection (SSI) is an infection occurring in an incisional wound within 30 days of surgery and significantly affects patients undergoing colorectal surgery. This study examined a multi-institutional dataset to determine risk factors for SSI following colorectal resection. Data on 386 patients who underwent colorectal resection in three institutions were accrued. Patients were identified using a prospective SSI database and hospital records. Data are presented as median (interquartile range), and logistic regression analysis was used to identify risk factors. Patients (21.5 %) developed a postoperative SSI. The median time to the development of SSI was 7 days (5-10). Of all infections, 67.5 % were superficial, 22.9 % were deep and 9.6 % were organ space. In univariate analysis, an ASA grade of II (RR 0.6, CI 0.3-0.9, P = 0.019), having an elective procedure (RR 0.4, CI 0.2-0.6, P < 0.001), using a laparoscopic approach (RR 0.5, CI 0.3-0.9, P = 0.019), having a daytime procedure (RR 0.3, CI 0.1-0.7, P = 0.006) and having a clean/contaminated wound (RR 0.4, CI 0.2-0.7, P = 0.001) were associated with reduced risk of SSI. In multivariate analysis, an ASA grade of IV (RR 3.9, CI 1.1-13.7, P = 0.034), a procedure duration over 3 h (RR 4.3, CI 2.3-8.2, P < 0.001) and undergoing a panproctocolectomy (RR 6.5, CI 1.0-40.9, P = 0.044) were independent risk factors for SSI. Those who developed an SSI had a longer duration of inpatient stay (22 days [16-31] vs 15 days [10-26], P < 0.001). Patients who develop an SSI have a longer duration of inpatient stay. Independent risk factors for SSI following colorectal resection include being ASA grade IV, having a procedure duration over 3 h, and undergoing a panproctocolectomy. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 3% |
Unknown | 33 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 18% |
Other | 4 | 12% |
Student > Doctoral Student | 3 | 9% |
Student > Postgraduate | 3 | 9% |
Student > Ph. D. Student | 3 | 9% |
Other | 5 | 15% |
Unknown | 10 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 50% |
Nursing and Health Professions | 3 | 9% |
Unspecified | 1 | 3% |
Mathematics | 1 | 3% |
Unknown | 12 | 35% |