| Title |
Acute kidney injury in neonatal encephalopathy: an evaluation of the AWAKEN database
|
|---|---|
| Published in |
Pediatric Nephrology, August 2018
|
| DOI | 10.1007/s00467-018-4068-2 |
| Pubmed ID | |
| Authors |
Megan J. Kirkley, Louis Boohaker, Russell Griffin, Danielle E. Soranno, Jason Gien, David Askenazi, Katja M. Gist |
| Abstract |
Acute kidney injury (AKI) is common in neonatal encephalopathy (NE) and is associated with worse outcomes. Our objectives were to determine the incidence, risk factors, and outcomes of AKI in infants with NE. We performed a retrospective analysis of infants ≥ 34 weeks' gestational age with a diagnosis of NE from the Analysis of Worldwide Acute Kidney injury Epidemiology in Neonates (AWAKEN) database. AKI was defined using the modified Kidney Disease Improving Global Outcomes criteria. Perinatal and postnatal factors were evaluated. Multivariate logistic and linear regressions were performed. One hundred and thirteen patients with NE were included. 41.6% (47) developed AKI. Being born outside the admitting institution (OR 4.3; 95% CI 1.2-14.8; p = 0.02), intrauterine growth restriction (OR 10.3, 95% CI 1.1-100.5; p = 0.04), and meconium at delivery (OR 2.8, 95% CI 1.04-7.7; p = 0.04) conferred increased odds of AKI. After controlling for confounders, infants with AKI stayed in the hospital an average of 8.5 days longer than infants without AKI (95% CI 0.79-16.2 days; p = 0.03). In this multi-national analysis, several important perinatal factors were associated with AKI and infants with both NE and AKI had longer length of stay than NE alone. Future research aimed at early AKI detection, renoprotective management strategies, and understanding the long-term renal consequences is warranted in this high-risk group of patients. |
X Demographics
The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 38% |
| India | 1 | 8% |
| Colombia | 1 | 8% |
| Canada | 1 | 8% |
| Unknown | 5 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 46% |
| Practitioners (doctors, other healthcare professionals) | 4 | 31% |
| Scientists | 2 | 15% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 69 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 12% |
| Researcher | 6 | 9% |
| Student > Postgraduate | 6 | 9% |
| Other | 5 | 7% |
| Student > Master | 5 | 7% |
| Other | 8 | 12% |
| Unknown | 31 | 45% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 28% |
| Psychology | 5 | 7% |
| Nursing and Health Professions | 4 | 6% |
| Unspecified | 2 | 3% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 33 | 48% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2023.
All research outputs
#2,213,040
of 24,468,058 outputs
Outputs from Pediatric Nephrology
#200
of 3,882 outputs
Outputs of similar age
#45,389
of 338,905 outputs
Outputs of similar age from Pediatric Nephrology
#5
of 87 outputs
Altmetric has tracked 24,468,058 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,882 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 94% of its peers.
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We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.