You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Relationship of muscle function to circulating myostatin, follistatin and GDF11 in older women and men
|
|---|---|
| Published in |
BMC Geriatrics, August 2018
|
| DOI | 10.1186/s12877-018-0888-y |
| Pubmed ID | |
| Authors |
Elizaveta Fife, Joanna Kostka, Łukasz Kroc, Agnieszka Guligowska, Małgorzata Pigłowska, Bartłomiej Sołtysik, Agnieszka Kaufman-Szymczyk, Krystyna Fabianowska-Majewska, Tomasz Kostka |
| Abstract |
Myostatin, its inhibitor follistatin, and growth/differentiation factor 11 (GDF11) have been proposed as factors that could potentially modify biological aging. The study aimed to test whether there is a relationship between these plasma circulating proteins and muscle strength, power and optimal shortening velocity (υopt) of older adults. The cross-sectional study included 56 women and 45 men aged 60 years and older. Every participant underwent examination which included anthropometric and bioimpedance analysis measurements, functional and cognitive performance tests, muscle strength of upper and lower extremities, muscle power testing with two different methods and blood analyses. Women had higher plasma levels of myostatin and GDF11 than men. Men had higher plasma level of follistatin than women. In women, plasma level of myostatin was negatively correlated with left handgrip strength and υopt. Follistatin was negatively correlated with maximum power output (Pmax), power relative to kg of body mass (Pmax∙kg- 1) (friction-loaded cycle ergometer) and power at 70% of the 1-repetition maximum (1RM) strength value (P70%) of leg press (Keiser pneumatic resistance training equipment), and positively correlated with the Timed Up & Go (TUG) test. GDF11 was negatively correlated with body mass, body mass index, waist circumference, fat mass and the percentage of body fat. In men, there were no significant correlations observed between circulating plasma proteins and muscle function measures. The circulating plasma myostatin and follistatin are negatively associated with muscle function in older women. There is stronger relationship between these proteins and muscle power than muscle strength. GDF11 has a higher association with the body mass and composition than muscle function in older women. |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 136 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 14% |
| Student > Ph. D. Student | 11 | 8% |
| Student > Master | 11 | 8% |
| Student > Doctoral Student | 11 | 8% |
| Researcher | 8 | 6% |
| Other | 25 | 18% |
| Unknown | 51 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 16% |
| Sports and Recreations | 15 | 11% |
| Nursing and Health Professions | 12 | 9% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Agricultural and Biological Sciences | 7 | 5% |
| Other | 15 | 11% |
| Unknown | 57 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2018.
All research outputs
#5,832,615
of 23,102,082 outputs
Outputs from BMC Geriatrics
#1,355
of 3,264 outputs
Outputs of similar age
#100,912
of 334,790 outputs
Outputs of similar age from BMC Geriatrics
#49
of 72 outputs
Altmetric has tracked 23,102,082 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 3,264 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,790 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.