| Title |
MicroRNAs as biomarkers and prospective therapeutic targets in colon and pancreatic cancers
|
|---|---|
| Published in |
Tumor Biology, November 2015
|
| DOI | 10.1007/s13277-015-4346-6 |
| Pubmed ID | |
| Authors |
Ganji Purnachandra Nagaraju, Appiya Santharam Madanraj, Sheik Aliya, Balney Rajitha, Olatunji Boladale Alese, Ekamber Kariali, Afroz Alam, Bassel F. El-Rayes |
| Abstract |
Colon and pancreatic cancers have high mortality rates due to early metastasis prior to the onset of symptoms. Screening tests for colorectal cancer are invasive and expensive. No effective screening is available for pancreatic cancer. Identification of biomarkers for early detection in both of these cancers is being extensively researched. MicroRNAs (miRNA) are small non-coding molecule biomarkers that regulate cancers. Measurement of miRNAs in pancreatic fluid or blood could be a preferred non-invasive screening method. The regulation of colon and pancreatic cancers by miRNA is complex. miRNA play a central role in inflammation, invasiveness, and tumor progression in these two cancers, as well as regulation of the NF-κB pathway. miRNA's evolving role in screening is also reviewed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 17% |
| Researcher | 8 | 15% |
| Student > Ph. D. Student | 7 | 13% |
| Professor > Associate Professor | 4 | 8% |
| Student > Doctoral Student | 4 | 8% |
| Other | 14 | 26% |
| Unknown | 7 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 30% |
| Biochemistry, Genetics and Molecular Biology | 8 | 15% |
| Agricultural and Biological Sciences | 6 | 11% |
| Unspecified | 3 | 6% |
| Nursing and Health Professions | 2 | 4% |
| Other | 6 | 11% |
| Unknown | 12 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2015.
All research outputs
#20,295,501
of 22,832,057 outputs
Outputs from Tumor Biology
#1,834
of 2,622 outputs
Outputs of similar age
#239,103
of 285,322 outputs
Outputs of similar age from Tumor Biology
#189
of 293 outputs
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