| Title |
New Insights into the Role of Exosomes in the Heart After Myocardial Infarction
|
|---|---|
| Published in |
Journal of Cardiovascular Translational Research, September 2018
|
| DOI | 10.1007/s12265-018-9831-z |
| Pubmed ID | |
| Authors |
Na Li, Luc Rochette, Yongxin Wu, Nathalie Rosenblatt-Velin |
| Abstract |
Intercellular communications play a pivotal role in several cardiac pathophysiological processes. One subtype of extracellular vesicles, so-called exosomes, became known as important intercellular communication mediators in the heart. Exosomes are lipid bilayer biological nanovesicles loaded with diverse proteins, lipids, and mRNAs/microRNAs. All major cardiac cell types can modulate recipient cellular function via the release of exosomes. After myocardial infarction (MI), exosomes, especially those secreted by different cardiac stem cells, have been shown to confer cardioprotective effects, activate regenerative signals, and participate into cardiac repair. In this review, we rapidly recall the biology of exosomes at the beginning. Then we summarize the exosomes secreted by different myocardial cells and their function in cardiac intercellular communication. At last, we discuss the role of these vesicles in cardiac repair after MI. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 69 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 14% |
| Researcher | 8 | 12% |
| Student > Doctoral Student | 8 | 12% |
| Student > Bachelor | 5 | 7% |
| Student > Postgraduate | 5 | 7% |
| Other | 9 | 13% |
| Unknown | 24 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 25% |
| Biochemistry, Genetics and Molecular Biology | 11 | 16% |
| Agricultural and Biological Sciences | 6 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Immunology and Microbiology | 1 | 1% |
| Other | 5 | 7% |
| Unknown | 25 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 September 2018.
All research outputs
#20,532,290
of 23,102,082 outputs
Outputs from Journal of Cardiovascular Translational Research
#499
of 580 outputs
Outputs of similar age
#292,485
of 335,868 outputs
Outputs of similar age from Journal of Cardiovascular Translational Research
#5
of 9 outputs
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