| Title |
Naltrexone: Not Just for Opioids Anymore
|
|---|---|
| Published in |
Journal of Medical Toxicology, November 2015
|
| DOI | 10.1007/s13181-015-0512-x |
| Pubmed ID | |
| Authors |
Daniel Sudakin |
| Abstract |
Naltrexone is a semi-synthetic opioid with competitive antagonist activity at mu opioid receptors. Its efficacy has been demonstrated in the treatment of alcohol and opioid dependence, but adherence to daily dosing has been recognized as a factor limiting long-term effectiveness. Recently, a long-acting injectable formulation of naltrexone has received FDA-approval for treating alcohol and opioid dependence. This article reviews the pharmacology of naltrexone, the current evidence supporting the use of extended-release naltrexone, and the clinical challenges in the induction of patients to this medication. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 111 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 25 | 23% |
| Researcher | 9 | 8% |
| Student > Master | 9 | 8% |
| Other | 8 | 7% |
| Student > Ph. D. Student | 7 | 6% |
| Other | 14 | 13% |
| Unknown | 39 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 24% |
| Psychology | 9 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 7% |
| Biochemistry, Genetics and Molecular Biology | 6 | 5% |
| Chemistry | 6 | 5% |
| Other | 15 | 14% |
| Unknown | 40 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2023.
All research outputs
#4,905,452
of 25,654,806 outputs
Outputs from Journal of Medical Toxicology
#302
of 731 outputs
Outputs of similar age
#61,691
of 297,950 outputs
Outputs of similar age from Journal of Medical Toxicology
#5
of 18 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 731 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.6. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,950 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.