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The Mechanisms of Inhibition of Advanced Glycation End Products Formation through Polyphenols in Hyperglycemic Condition

Overview of attention for article published in Planta Medica, November 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

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3 X users
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3 patents

Citations

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77 Dimensions

Readers on

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155 Mendeley
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Title
The Mechanisms of Inhibition of Advanced Glycation End Products Formation through Polyphenols in Hyperglycemic Condition
Published in
Planta Medica, November 2015
DOI 10.1055/s-0035-1558086
Pubmed ID
Authors

Shahpour Khangholi, Fadzilah Adibah Abdul Majid, Najat Jabbar Ahmed Berwary, Farediah Ahmad, Ramlan Bin Abd Aziz

Abstract

Glycation, the non-enzymatic binding of glucose to free amino groups of an amino acid, yields irreversible heterogeneous compounds known as advanced glycation end products. Those products play a significant role in diabetic complications. In the present article we briefly discuss the contribution of advanced glycation end products to the pathogenesis of diabetic complications, such as atherosclerosis, diabetic retinopathy, nephropathy, neuropathy, and wound healing. Then we mention the various mechanisms by which polyphenols inhibit the formation of advanced glycation end products. Finally, recent supporting documents are presented to clarify the inhibitory effects of polyphenols on the formation of advanced glycation end products. Phytochemicals apply several antiglycation mechanisms, including glucose metabolism, amelioration of oxidative stress, scavenging of dicarbonyl species, and up/down-regulation of gene expression. To utilize polyphenols in order to remedy diabetic complications, we must explore, examine and clarify the action mechanisms of the components of polyphenols.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 154 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 15%
Student > Master 20 13%
Student > Bachelor 16 10%
Researcher 15 10%
Student > Doctoral Student 12 8%
Other 21 14%
Unknown 47 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 15%
Biochemistry, Genetics and Molecular Biology 19 12%
Pharmacology, Toxicology and Pharmaceutical Science 14 9%
Medicine and Dentistry 11 7%
Nursing and Health Professions 7 5%
Other 26 17%
Unknown 55 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 August 2023.
All research outputs
#3,910,455
of 23,861,043 outputs
Outputs from Planta Medica
#334
of 2,947 outputs
Outputs of similar age
#52,797
of 288,405 outputs
Outputs of similar age from Planta Medica
#5
of 23 outputs
Altmetric has tracked 23,861,043 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,947 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,405 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.