| Title |
Health-related quality of life in people with advanced dementia: a comparison of EQ-5D-5L and QUALID instruments
|
|---|---|
| Published in |
Quality of Life Research, September 2018
|
| DOI | 10.1007/s11136-018-1987-0 |
| Pubmed ID | |
| Authors |
Elizaveta Sopina, Lynn Chenoweth, Tim Luckett, Meera Agar, Georgina M. Luscombe, Patricia M. Davidson, Constance D. Pond, Jane Phillips, Stephen Goodall |
| Abstract |
Assessing health-related quality of life (HRQOL) in people with advanced dementia is challenging but important for informed decision-making. Proxy measurement of this construct is difficult and is often rated lower than self-report. Accurate proxy rating of quality of life in dementia is related to identification of concepts important to the person themselves, as well as the sensitivity of the measures used. The main aim of this study was to compare the performance of two instruments-QUALID and EQ-5D-5L-on measuring HRQOL in people with advanced dementia. In a sub-study nested within a cluster-RCT we collected proxy(nurse)-completed EQ-5D-5L and QUALID measures at baseline, 3, 6, 9 and 12 months' follow-up for people with advanced dementia, residing in 20 nursing homes across Australia. Spearman's rank correlations, partial correlations and linear regressions were used to assess the relationship between the HRQOL instrument scores and their changes over time. The mean weight from 284 people for the EQ-5D-5L and QUALID at baseline were 0.004 (95% CI - 0.026, 0.033) and 24.98 (95% CI 24.13, 25.82), respectively. At 12 months' follow-up, 115 participants remained alive. EQ-5D-5L weights and QUALID scores at baseline and at follow-up were moderately correlated (r = - 0.437; p < 0.001 at 12 months). Changes within QUALID and EQ-5D-5L across the same follow-up periods were also correlated (r = - 0.266; p = 0.005). The regression analyses support these findings. Whilst these quality of life instruments demonstrated moderate correlation, the EQ-5D-5L does not appear to capture all aspects of quality of life that are relevant to people with advanced dementia and we cannot recommend the use of this instrument for use within this population. The QUALID appears to be a more suitable instrument for measuring HRQOL in people with severe dementia, but is not preference-based, which limits its application in economic evaluations of dementia care. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 5 | 29% |
| Canada | 3 | 18% |
| Denmark | 3 | 18% |
| Curaçao | 1 | 6% |
| United Kingdom | 1 | 6% |
| Unknown | 4 | 24% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 53% |
| Scientists | 5 | 29% |
| Practitioners (doctors, other healthcare professionals) | 2 | 12% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 70 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 17% |
| Researcher | 8 | 11% |
| Student > Bachelor | 7 | 10% |
| Student > Ph. D. Student | 6 | 9% |
| Student > Postgraduate | 5 | 7% |
| Other | 10 | 14% |
| Unknown | 22 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 19 | 27% |
| Medicine and Dentistry | 14 | 20% |
| Social Sciences | 5 | 7% |
| Psychology | 2 | 3% |
| Agricultural and Biological Sciences | 1 | 1% |
| Other | 7 | 10% |
| Unknown | 22 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2019.
All research outputs
#2,811,232
of 22,959,818 outputs
Outputs from Quality of Life Research
#223
of 2,910 outputs
Outputs of similar age
#59,498
of 335,480 outputs
Outputs of similar age from Quality of Life Research
#8
of 83 outputs
Altmetric has tracked 22,959,818 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,910 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,480 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.