| Title |
Treatment of Cryptosporidium: What We Know, Gaps, and the Way Forward
|
|---|---|
| Published in |
Current Tropical Medicine Reports, August 2015
|
| DOI | 10.1007/s40475-015-0056-9 |
| Pubmed ID | |
| Authors |
Hayley Sparks, Gayatri Nair, Alejandro Castellanos-Gonzalez, A. Clinton White |
| Abstract |
Cryptosporidiosis is increasingly recognized as an important global health concern. While initially reported in immunocompromised such as AIDS patients, cryptosporidiosis has now been documented as a major cause of childhood diarrhea and an important factor in childhood malnutrition. Currently, nitazoxanide is the only proven anti-parasitic treatment for Cryptosporidium infections. However, it is not effective in severely immunocompromised patients and there is limited data in infants. Immune reconstitution or decreased immunosuppression is critical to therapy in AIDS and transplant patients. This limitation of treatment options presents a major public health challenge given the important burden of disease. Repurposing of drugs developed for other indications and development of inhibitors for novel targets offer hope for improved therapies, but none have advanced to clinical studies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 174 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 40 | 23% |
| Student > Ph. D. Student | 18 | 10% |
| Researcher | 14 | 8% |
| Student > Master | 12 | 7% |
| Student > Doctoral Student | 9 | 5% |
| Other | 27 | 16% |
| Unknown | 54 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 29 | 17% |
| Medicine and Dentistry | 22 | 13% |
| Agricultural and Biological Sciences | 18 | 10% |
| Immunology and Microbiology | 18 | 10% |
| Chemistry | 7 | 4% |
| Other | 22 | 13% |
| Unknown | 58 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2023.
All research outputs
#7,224,351
of 22,833,393 outputs
Outputs from Current Tropical Medicine Reports
#48
of 137 outputs
Outputs of similar age
#85,040
of 264,278 outputs
Outputs of similar age from Current Tropical Medicine Reports
#4
of 6 outputs
Altmetric has tracked 22,833,393 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 137 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,278 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.