Title |
The breast cancer genome - a key for better oncology
|
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Published in |
BMC Cancer, November 2011
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DOI | 10.1186/1471-2407-11-501 |
Pubmed ID | |
Authors |
Hans Kristian Moen Vollan, Carlos Caldas |
Abstract |
Molecular classification has added important knowledge to breast cancer biology, but has yet to be implemented as a clinical standard. Full sequencing of breast cancer genomes could potentially refine classification and give a more complete picture of the mutational profile of cancer and thus aid therapy decisions. Future treatment guidelines must be based on the knowledge derived from histopathological sub-classification of tumors, but with added information from genomic signatures when properly clinically validated. The objective of this article is to give some background on molecular classification, the potential of next generation sequencing, and to outline how this information could be implemented in the clinic. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | 4% |
Portugal | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 45 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 20% |
Researcher | 9 | 18% |
Student > Master | 6 | 12% |
Other | 5 | 10% |
Student > Postgraduate | 4 | 8% |
Other | 8 | 16% |
Unknown | 7 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 35% |
Medicine and Dentistry | 12 | 24% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Social Sciences | 3 | 6% |
Psychology | 2 | 4% |
Other | 5 | 10% |
Unknown | 7 | 14% |