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Improved Surgical Success of Combined Glaucoma Tube Shunt and Retisert® Implantation in Uveitic Eyes: A Retrospective Study

Overview of attention for article published in Ophthalmology and Therapy, November 2015
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Title
Improved Surgical Success of Combined Glaucoma Tube Shunt and Retisert® Implantation in Uveitic Eyes: A Retrospective Study
Published in
Ophthalmology and Therapy, November 2015
DOI 10.1007/s40123-015-0041-3
Pubmed ID
Authors

Daniel B. Moore, Sandra Stinnett, Glenn J. Jaffe, Sanjay Asrani

Abstract

The purpose of this study was to determine whether the outcomes following placement of a fluocinolone acetonide implant (Retisert(®); Bausch & Lomb, Inc.) combined with an Ahmed™ glaucoma valve (New World Medical, Inc.) in eyes with uveitic glaucoma (UG Retisert) were different when compared to an Ahmed valve alone in eyes with uveitic glaucoma or primary open angle glaucoma (UG non-Retisert and POAG, respectively). Retrospective, interventional study of consecutive uveitic and OAG eyes undergoing Ahmed valve (AV) implantation with or without combined Retisert insertion at a single academic center between 2009 and 2012. Surgical success was defined as intraocular pressure (IOP) between 5 and 18 mmHg and greater than 20% reduction of IOP at two consecutive visits without need for additional IOP-lowering medications or surgical procedures. Secondary outcome measures included IOP and number of glaucoma medications. Sixty eyes of 60 patients (22 UG Retisert, 16 UG non-Retisert, 22 POAG) were included. Mean ± standard deviation surgical success duration was significantly greater in UG Retisert eyes, 629 ± 53 days, compared to those with UG non-Retisert, 361 ± 37 days, and POAG, 472 ± 65 days (P = 0.034). At 24 months, the mean IOP was 11.7, 12.1, and 15.0 mmHg and the average patient was on 1.45, 0.71, and 2.00 medications in the UG Retisert, UG non-Retisert, and POAG valve groups, respectively. Retisert implants when combined with AV in uveitic glaucoma had a longer duration of surgical success than uveitic or POAG treated with AV insertion alone.

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Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 30%
Student > Bachelor 2 20%
Student > Ph. D. Student 1 10%
Unspecified 1 10%
Student > Doctoral Student 1 10%
Other 0 0%
Unknown 2 20%
Readers by discipline Count As %
Medicine and Dentistry 7 70%
Unspecified 1 10%
Unknown 2 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2015.
All research outputs
#20,296,405
of 22,833,393 outputs
Outputs from Ophthalmology and Therapy
#560
of 571 outputs
Outputs of similar age
#239,487
of 285,891 outputs
Outputs of similar age from Ophthalmology and Therapy
#5
of 5 outputs
Altmetric has tracked 22,833,393 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 571 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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