| Title |
Randomized controlled pilot trial of mindfulness-based stress reduction for breast and colorectal cancer survivors: effects on cancer-related cognitive impairment
|
|---|---|
| Published in |
Journal of Cancer Survivorship, November 2015
|
| DOI | 10.1007/s11764-015-0494-3 |
| Pubmed ID | |
| Authors |
Shelley A. Johns, Diane Von Ah, Linda F. Brown, Kathleen Beck-Coon, Tasneem L. Talib, Jennifer M. Alyea, Patrick O. Monahan, Yan Tong, Laura Wilhelm, R. Brian Giesler |
| Abstract |
Cancer-related cognitive impairment (CRCI) is a common, fatigue-related symptom that disrupts cancer survivors' quality of life. Few interventions for CRCI exist. As part of a randomized pilot study targeting cancer-related fatigue, the effects of mindfulness-based stress reduction (MBSR) on survivors' cognitive outcomes were investigated. Breast and colorectal cancer survivors (n = 71) with moderate-to-severe fatigue were randomized to MBSR (n = 35) or a fatigue education and support (ES; n = 36) condition. The Attentional Function Index (AFI) and the Stroop test were used to assess survivors' cognitive function at baseline (T1), after the 8-week intervention period (T2), and 6 months later (T3) using intent-to-treat analysis. Mediation analyses were performed to explore mechanisms of intervention effects on cognitive functioning. MBSR participants reported significantly greater improvement on the AFI total score compared to ES participants at T2 (d = 0.83, p = 0.001) and T3 (d = 0.55, p = 0.021). MBSR also significantly outperformed ES on most AFI subscales, although both groups improved over time. MBSR produced greater Stroop accuracy rates relative to ES at T2 (r = 0.340, p = 0.005) and T3 (r = 0.280, p = 0.030), with improved accuracy over time only for the MBSR group. There were no significant differences in Stroop reaction time between groups. Improvements in mindfulness mediated the effect of group (e.g., MBSR vs. ES) on AFI total score at T2 and T3. Additional randomized trials with more comprehensive cognitive measures are warranted to definitively assess the efficacy of MBSR for CRCI. This pilot study has important implications for all cancer survivors as it is the first published trial to show that MBSR offers robust and durable improvements in CRCI. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 30% |
| United Kingdom | 2 | 20% |
| Unknown | 5 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 80% |
| Science communicators (journalists, bloggers, editors) | 1 | 10% |
| Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 295 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Unknown | 293 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 47 | 16% |
| Student > Ph. D. Student | 36 | 12% |
| Student > Bachelor | 30 | 10% |
| Student > Doctoral Student | 27 | 9% |
| Researcher | 24 | 8% |
| Other | 53 | 18% |
| Unknown | 78 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 74 | 25% |
| Nursing and Health Professions | 41 | 14% |
| Medicine and Dentistry | 29 | 10% |
| Social Sciences | 15 | 5% |
| Neuroscience | 11 | 4% |
| Other | 32 | 11% |
| Unknown | 93 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 143. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2020.
All research outputs
#276,144
of 24,641,327 outputs
Outputs from Journal of Cancer Survivorship
#6
of 1,104 outputs
Outputs of similar age
#4,368
of 396,856 outputs
Outputs of similar age from Journal of Cancer Survivorship
#1
of 20 outputs
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