Title |
A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders
|
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Published in |
Neuroscience & Biobehavioral Reviews, November 2011
|
DOI | 10.1016/j.neubiorev.2011.10.008 |
Pubmed ID | |
Authors |
Ruth C.M. Philip, Maria R. Dauvermann, Heather C. Whalley, Katie Baynham, Stephen M. Lawrie, Andrew C. Stanfield |
Abstract |
Recent years have seen a rapid increase in the investigation of autism spectrum disorders (ASD) through the use of functional magnetic resonance imaging (fMRI). We carried out a systematic review and ALE meta-analysis of fMRI studies of ASD. A disturbance to the function of social brain regions is among the most well replicated finding. Differences in social brain activation may relate to a lack of preference for social stimuli as opposed to a primary dysfunction of these regions. Increasing evidence points towards a lack of effective integration of distributed functional brain regions and disruptions in the subtle modulation of brain function in relation to changing task demands in ASD. Limitations of the literature to date include the use of small sample sizes and the restriction of investigation to primarily high functioning males with autism. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 50% |
Spain | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 10 | 2% |
United Kingdom | 5 | <1% |
Germany | 2 | <1% |
Hong Kong | 2 | <1% |
Netherlands | 2 | <1% |
Switzerland | 1 | <1% |
Italy | 1 | <1% |
France | 1 | <1% |
Portugal | 1 | <1% |
Other | 8 | 1% |
Unknown | 625 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 130 | 20% |
Student > Master | 100 | 15% |
Researcher | 92 | 14% |
Student > Bachelor | 76 | 12% |
Student > Doctoral Student | 49 | 7% |
Other | 100 | 15% |
Unknown | 111 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 213 | 32% |
Neuroscience | 87 | 13% |
Medicine and Dentistry | 69 | 10% |
Agricultural and Biological Sciences | 33 | 5% |
Social Sciences | 21 | 3% |
Other | 81 | 12% |
Unknown | 154 | 23% |