| Title |
Q&A: Mesenchymal stem cells — where do they come from and is it important?
|
|---|---|
| Published in |
BMC Biology, November 2015
|
| DOI | 10.1186/s12915-015-0212-7 |
| Pubmed ID | |
| Authors |
Iain R. Murray, Bruno Péault |
| Abstract |
Mesenchymal stem - or stromal - cells (MSCs) have been administered in hundreds of clinical trials for multiple indications, making them some of the most commonly used selected regenerative cells. Paradoxically, MSCs have also long remained the least characterized stem cells regarding native identity and natural function, being isolated retrospectively in long-term culture. Recent years have seen progress in our understanding of the natural history of these cells, and candidate native MSCs have been identified within fetal and adult organs. Beyond basic knowledge, deciphering the biology of innate MSCs may have important positive consequences for the therapeutic use of these cells. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 25% |
| United Kingdom | 2 | 25% |
| Switzerland | 1 | 13% |
| Unknown | 3 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 63% |
| Scientists | 3 | 38% |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | <1% |
| Malaysia | 1 | <1% |
| France | 1 | <1% |
| Unknown | 148 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 21% |
| Student > Bachelor | 25 | 17% |
| Researcher | 21 | 14% |
| Student > Master | 18 | 12% |
| Student > Doctoral Student | 6 | 4% |
| Other | 16 | 11% |
| Unknown | 33 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 26% |
| Medicine and Dentistry | 29 | 19% |
| Agricultural and Biological Sciences | 23 | 15% |
| Immunology and Microbiology | 6 | 4% |
| Veterinary Science and Veterinary Medicine | 4 | 3% |
| Other | 15 | 10% |
| Unknown | 34 | 23% |