To investigate health professionals' opinions toward offering NIPT as first-tier screening test regardless of pregnant women's risk, and toward a potential broader range of disorders.
A questionnaire completed by obstetric health professionals (n = 240) after an in-service NIPT training in the West and North of the Netherlands.
The majority (73%) of respondents favored replacing first trimester combined test (FCT) by NIPT, although 43% preferred to maintain nuchal translucency (NT) measurement. Many respondents believed that replacing FCT by NIPT would only have advantages (57%), would lead to more pregnant women opting for prenatal testing (69%) and would simplify counseling (47%). Differences in attitudes toward counseling between health professionals were observed. When considering NIPT to screen for broader range of disorders, the majority (92%) thought this should include disorders characterized by neonatal death, whereas 52% of the respondents favored testing for fetomaternal risk factors. Overall, 47% thought screening should be offered as a fixed list of disorders.
Most health professionals favor NIPT instead of FCT, but prefer to maintain NT measurement. If NIPT becomes available as a first-tier screening test, attention remains necessary to ensure that pregnant women make well-informed decisions in line with the aim of prenatal screening.