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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Rapid, Single-Cell Electrochemical Detection of Mycobacterium tuberculosis Using Colloidal Gold Nanoparticles
|
|---|---|
| Published in |
Analytical Chemistry, October 2015
|
| DOI | 10.1021/acs.analchem.5b03121 |
| Pubmed ID | |
| Authors |
Benjamin Y. C. Ng, Wei Xiao, Nicholas P. West, Eugene J. H. Wee, Yuling Wang, Matt Trau |
| Abstract |
Tuberculosis (TB) remains a global health threat, with over a third of the world population suffering from the disease, and 1.5 million deaths due to the disease in 2013 alone. Despite significant advances in TB detection strategies in recent years, a bigger push towards detecting TB in the shortest and easiest way possible at the point-of-care (POC) is still in demand. To this end, we have designed a simple yet rapid and sensitive bioassay that detects Mtb DNA electrochemically using colloidal gold nanoparticles. This assay couples rapid isothermal amplification of target DNA that is specific to Mtb with gold nanoparticle electrochemistry on disposable screen printed carbon electrodes. The assay is capable of detecting a positive differential pulse voltammetry (DPV) response from as low as 1 CFU of Mtb bacilli DNA input material, and having shown its exquisite sensitivity over a conventional gel based readout. The translation of our assay onto a portable potentiostat was also demonstrated, with promising results. We believe that our assay has significant potential for translation into broader bioassay applications or development as a POC diagnostic tool. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 67% |
| Finland | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| India | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 83 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 35% |
| Student > Master | 11 | 13% |
| Researcher | 10 | 12% |
| Student > Doctoral Student | 8 | 9% |
| Student > Bachelor | 8 | 9% |
| Other | 7 | 8% |
| Unknown | 12 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 20 | 23% |
| Engineering | 12 | 14% |
| Agricultural and Biological Sciences | 10 | 12% |
| Biochemistry, Genetics and Molecular Biology | 10 | 12% |
| Medicine and Dentistry | 7 | 8% |
| Other | 12 | 14% |
| Unknown | 15 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2016.
All research outputs
#13,450,711
of 22,833,393 outputs
Outputs from Analytical Chemistry
#17,963
of 26,480 outputs
Outputs of similar age
#130,106
of 275,407 outputs
Outputs of similar age from Analytical Chemistry
#116
of 226 outputs
Altmetric has tracked 22,833,393 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 26,480 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,407 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 226 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.