| Title |
Localization of Galectins within Glycocalyx
|
|---|---|
| Published in |
Biochemistry, June 2018
|
| DOI | 10.1134/s000629791806010x |
| Pubmed ID | |
| Authors |
E. M. Rapoport, V. K. Matveeva, O. A. Vokhmyanina, I. M. Belyanchikov, H.-J. Gabius, N. V. Bovin |
| Abstract |
Galectins are involved in various biological processes, e.g. cell-cell and cell-matrix adhesion and the transmission of cellular signals. Despite the diversity of functions, little is known about the nature of their physiological cognate ligands on the cell surface and the localization of galectins in the glycocalyx, although this information is important for understanding the functional activity of galectins. In this work, localization of endogenous and exogenously loaded galectins in the glycocalyx was studied. The following main conclusions are drawn: 1) galectins are not evenly distributed within the glycocalyx, they are accumulated in patches. Patching is not the result of a cross-linking of cellular glycans by galectins. Instead, patch-wise localization is the consequence of irregular distribution of glycans forming the glycocalyx; 2) galectins are accumulated in the inner zone of the glycocalyx rather than at its outer face or directly in vicinity of the cell membrane; 3) patches are not associated with cell rafts. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 3 | 23% |
| Student > Bachelor | 2 | 15% |
| Researcher | 2 | 15% |
| Student > Master | 1 | 8% |
| Professor | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 4 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 31% |
| Chemistry | 2 | 15% |
| Immunology and Microbiology | 1 | 8% |
| Agricultural and Biological Sciences | 1 | 8% |
| Unknown | 5 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2018.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from Biochemistry
#19,491
of 22,293 outputs
Outputs of similar age
#220,450
of 341,432 outputs
Outputs of similar age from Biochemistry
#83
of 135 outputs
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