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Trained immunity: a new avenue for tuberculosis vaccine development

Overview of attention for article published in Journal of Internal Medicine, November 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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6 X users
facebook
1 Facebook page

Citations

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44 Dimensions

Readers on

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160 Mendeley
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Title
Trained immunity: a new avenue for tuberculosis vaccine development
Published in
Journal of Internal Medicine, November 2015
DOI 10.1111/joim.12449
Pubmed ID
Authors

M Lerm, M G Netea

Abstract

Adaptive immunity towards tuberculosis (TB) has been extensively studied for many years. In addition, in recent years the profound contribution of innate immunity to host defence against this disease has become evident. The discovery of pattern recognition receptors, which allow innate immunity to tailor its response to different infectious agents, has challenged the view that this arm of immunity is nonspecific. Evidence is now accumulating that innate immunity can remember a previous exposure to a microorganism and respond differently during a second exposure. Although the specificity and memory of innate immunity cannot compete with the highly sophisticated adaptive immune response, its contribution to host defence against infection and to vaccine-induced immunity should not be underestimated and needs to be explored. Here, we present the concept of trained immunity and discuss how this may contribute to new avenues for control of TB.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 160 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 <1%
Ireland 1 <1%
Norway 1 <1%
Unknown 157 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 18%
Student > Master 29 18%
Student > Bachelor 25 16%
Researcher 17 11%
Student > Doctoral Student 9 6%
Other 21 13%
Unknown 30 19%
Readers by discipline Count As %
Immunology and Microbiology 42 26%
Agricultural and Biological Sciences 26 16%
Biochemistry, Genetics and Molecular Biology 25 16%
Medicine and Dentistry 20 13%
Nursing and Health Professions 3 2%
Other 12 8%
Unknown 32 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2022.
All research outputs
#7,373,530
of 24,542,484 outputs
Outputs from Journal of Internal Medicine
#1,232
of 3,046 outputs
Outputs of similar age
#108,906
of 396,862 outputs
Outputs of similar age from Journal of Internal Medicine
#11
of 19 outputs
Altmetric has tracked 24,542,484 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 3,046 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,862 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.