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Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

Overview of attention for book
Cover of 'Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to microRNAs: Biogenesis, Action, Relevance of Tissue microRNAs in Disease Pathogenesis, Diagnosis and Therapy-The Concept of Circulating microRNAs.
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    Chapter 2 Extracellular microRNAs in Membrane Vesicles and Non-vesicular Carriers
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    Chapter 3 Technical Aspects Related to the Analysis of Circulating microRNAs.
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    Chapter 4 Circulating Blood-Borne microRNAs as Biomarkers in Solid Tumors.
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    Chapter 5 Circulating microRNA as Biomarkers in Hematological Malignancies.
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    Chapter 6 Circulating microRNAs as Biomarkers in Cardiovascular Diseases.
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    Chapter 7 Circulating microRNAs in Neurodegenerative Diseases.
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    Chapter 8 Circulating Extracellular microRNA in Systemic Autoimmunity.
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    Chapter 9 Circulating microRNAs in Inflammatory Bowel Diseases.
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    Chapter 10 Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation.
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    Chapter 11 Diagnostic Relevance of microRNAs in Other Body Fluids Including Urine, Feces, and Saliva.
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    Chapter 12 Circulating microRNAs as Hormones: Intercellular and Inter-organ Conveyors of Epigenetic Information?
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    Chapter 13 Are Circulating microRNAs Involved in Tumor Surveillance?
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    Chapter 14 Hypothetic Interindividual and Interspecies Relevance of microRNAs Released in Body Fluids.
Attention for Chapter 2: Extracellular microRNAs in Membrane Vesicles and Non-vesicular Carriers
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Citations

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Chapter title
Extracellular microRNAs in Membrane Vesicles and Non-vesicular Carriers
Chapter number 2
Book title
Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance
Published in
EXS, January 2015
DOI 10.1007/978-3-0348-0955-9_2
Pubmed ID
26608198
Book ISBNs
978-3-03-480953-5, 978-3-03-480955-9
Authors

Coenen-Stass, Anna M L, Mäger, Imre, Wood, Mathew J A, Anna M. L. Coenen-Stass, Imre Mäger, Mathew J. A. Wood

Abstract

Great excitement has surrounded the finding that small RNAs are stable in various biofluids and carry specific signatures reflecting physiological and pathological states. In this chapter, we briefly describe the impact of this revolutionary discovery and introduce different subclasses of circulating microRNAs based on their mode of transport. Subsequently, we review the current state-of-the art knowledge on microRNA selection for export, secretion and possible uptake mechanisms and their potential function in circulation. Furthermore, we give an overview on the possible use of cell-free microRNAs as biomarkers and as therapeutic targets. Overall, we aim to highlight open questions and address some of the pitfalls of current extracellular RNA research.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 27%
Student > Ph. D. Student 2 18%
Unspecified 1 9%
Student > Doctoral Student 1 9%
Lecturer > Senior Lecturer 1 9%
Other 2 18%
Unknown 1 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 55%
Agricultural and Biological Sciences 2 18%
Unspecified 1 9%
Medicine and Dentistry 1 9%
Unknown 1 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2016.
All research outputs
#14,242,087
of 22,834,308 outputs
Outputs from EXS
#51
of 94 outputs
Outputs of similar age
#186,830
of 353,194 outputs
Outputs of similar age from EXS
#2
of 14 outputs
Altmetric has tracked 22,834,308 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 94 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,194 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.

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