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Mendeley readers
Attention Score in Context
| Title |
Association of alcohol consumption with allergic disease and asthma: a multi‐centre Mendelian randomization analysis
|
|---|---|
| Published in |
Addiction, October 2018
|
| DOI | 10.1111/add.14438 |
| Pubmed ID | |
| Authors |
Tea Skaaby, Tuomas O. Kilpeläinen, Amy E. Taylor, Yuvaraj Mahendran, Andrew Wong, Tarunveer S. Ahluwalia, Lavinia Paternoster, Stella Trompet, David J. Stott, Claudia Flexeder, Ang Zhou, Guy Brusselle, Ayesha Sajjad, Lies Lahousse, Henning Tiemeier, Christian Theil Have, Betina H. Thuesen, Line Lund Kårhus, Line Tang Møllehave, Katja Biering Leth‐Møller, Daniel Mønsted Shabanzadeh, Arturo Gonzalez‐Quintela, Chris Power, Elina Hyppönen, Diana Kuh, Rebecca Hardy, Thomas Meitinger, J. Wouter Jukema, Uwe Völker, Matthias Nauck, Henry Völzke, Nele Friedrich, Tobias N. Bonten, Raymond Noordam, Dennis O. Mook‐Kanamori, Janne S. Tolstrup, Christian Taube, Annette Peters, Harald Grallert, Konstantin Strauch, Holger Schulz, Niels Grarup, Torben Hansen, Oluf Pedersen, Stephen Burgess, Marcus R. Munafò, Allan Linneberg |
| Abstract |
To use the rs1229984 variant associated with alcohol consumption as an instrument for alcohol consumption to test the causality of the association of alcohol consumption with hay fever, asthma, allergic sensitization, and serum total IgE. Observational and Mendelian randomization analyses using genetic variants as unbiased markers of exposure to estimate causal effects, subject to certain assumptions. Europe. We included a total of 466434 persons aged 15-82 years from 17 population-based studies conducted from 1997-2015. The rs1229984 (ADH1B) was genotyped, alcohol consumption, hay fever and asthma were self-reported. Specific and total IgE were measured from serum samples. Observational analyses showed that ever-drinking vs. non-drinking, but not amount of alcohol intake, was positively associated with hay fever and inversely associated with asthma but not with allergic sensitization, or serum total IgE. However, Mendelian randomization analyses did not suggest that the observational associations are causal. The causal odds ratio (OR) per genetically assessed unit of alcohol/week was an OR=0.91 (95% confidence interval (CI): 0.81, 1.02; p=0.101) for hay fever, an OR=0.90 (95% CI: 0.79, 1.02; p=0.095) for asthma, an OR=0.97 (95% CI: 0.80, 1.17; p=0.763) for allergic sensitization, and a 4.7% change (95% CI: -5.5%, 14.9%; p=0.366) for total IgE. Ever-drinking vs. not drinking was in observational analyses positively associated with hay fever, and negatively associated with asthma. However, the Mendelian randomization results were not consistent with these associations being causal. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 14% |
| Student > Ph. D. Student | 6 | 10% |
| Student > Bachelor | 6 | 10% |
| Professor | 5 | 8% |
| Student > Master | 4 | 6% |
| Other | 13 | 21% |
| Unknown | 20 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 21% |
| Nursing and Health Professions | 7 | 11% |
| Psychology | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Environmental Science | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 25 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2020.
All research outputs
#15,102,803
of 24,417,958 outputs
Outputs from Addiction
#5,243
of 6,125 outputs
Outputs of similar age
#193,887
of 355,879 outputs
Outputs of similar age from Addiction
#52
of 58 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,125 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.9. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 355,879 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.