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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A single-blind, randomised controlled trial on the effects of lithium and quetiapine monotherapy on the trajectory of cognitive functioning in first episode mania: A 12-month follow-up study
|
|---|---|
| Published in |
European Psychiatry, March 2020
|
| DOI | 10.1016/j.eurpsy.2015.09.460 |
| Pubmed ID | |
| Authors |
R. Daglas, S.M. Cotton, K. Allott, M. Yücel, C.A. Macneil, M.K. Hasty, B. Murphy, C. Pantelis, K.T. Hallam, L.P. Henry, P. Conus, A. Ratheesh, L. Kader, M.TH. Wong, P.D. McGorry, M. Berk |
| Abstract |
Cognitive deficits have been reported during the early stages of bipolar disorder; however, the role of medication on such deficits remains unclear. The aim of this study was to compare the effects of lithium and quetiapine monotherapy on cognitive performance in people following first episode mania. The design was a single-blind, randomised controlled trial on a cohort of 61 participants following first episode mania. Participants received either lithium or quetiapine monotherapy as maintenance treatment over a 12-month follow-up period. The groups were compared on performance outcomes using an extensive cognitive assessment battery conducted at baseline, month 3 and month 12 follow-up time-points. There was a significant interaction between group and time in phonemic fluency at the 3-month and 12-month endpoints, reflecting greater improvements in performance in lithium-treated participants relative to quetiapine-treated participants. After controlling for multiple comparisons, there were no other significant interactions between group and time for other measures of cognition. Although the effects of lithium and quetiapine treatment were similar for most cognitive domains, the findings imply that early initiation of lithium treatment may benefit the trajectory of cognition, specifically verbal fluency in young people with bipolar disorder. Given that cognition is a major symptomatic domain of bipolar disorder and has substantive effects on general functioning, the ability to influence the trajectory of cognitive change is of considerable clinical importance. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 112 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 15% |
| Student > Master | 16 | 14% |
| Student > Ph. D. Student | 15 | 13% |
| Other | 12 | 11% |
| Researcher | 11 | 10% |
| Other | 18 | 16% |
| Unknown | 23 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 27 | 24% |
| Psychology | 24 | 21% |
| Neuroscience | 9 | 8% |
| Nursing and Health Professions | 4 | 4% |
| Agricultural and Biological Sciences | 4 | 4% |
| Other | 12 | 11% |
| Unknown | 32 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2017.
All research outputs
#2,881,183
of 22,834,308 outputs
Outputs from European Psychiatry
#248
of 2,034 outputs
Outputs of similar age
#68,541
of 366,765 outputs
Outputs of similar age from European Psychiatry
#135
of 1,128 outputs
Altmetric has tracked 22,834,308 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,034 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 366,765 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 1,128 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.