| Title |
Systematic review of pre-clinical chronic myeloid leukaemia
|
|---|---|
| Published in |
International Journal of Hematology, September 2018
|
| DOI | 10.1007/s12185-018-2528-x |
| Pubmed ID | |
| Authors |
Jew Win Kuan, Anselm Ting Su, Chooi Fun Leong, Motomi Osato, Goro Sashida |
| Abstract |
Studies of a provisional entity pre-clinical chronic myeloid leukaemia (CML), which precedes chronic phase (CP) without leucocytosis or blood/marrow feature of CML CP, has been increasing. To perform a systematic review of pre-clinical CML and analysis the data relevant to disease progression to CML CP. We performed a literature search on 16 July 2017 using EBSCOhost Research Databases interface and Western Pacific Region Index Medicus. Two authors selected the studies, extracted the data and evaluated the quality of studies using an 8-item tool, independently. The outcomes were percentage of Philadelphia chromosome in the number of metaphases examined (Ph%), correlation between Ph% and blood count and time progress to CML. Our initial search returned 4770 studies. A total of 10 studies with a total 17 subjects were included. The lowest Ph%, which eventually progresses to CML, was 10%. Absolute basophil count seemed to correlate better with Ph% compared to total white cell and absolute eosinophil count. The time from the first documented pre-clinical CML to CML ranged from 12 to 48 months. The overall quality of the included studies was average. This is the first systematic review on pre-clinical CML. This entity requires additional large-scale studies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 29 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 17% |
| Student > Postgraduate | 2 | 7% |
| Researcher | 2 | 7% |
| Student > Doctoral Student | 1 | 3% |
| Other | 1 | 3% |
| Other | 2 | 7% |
| Unknown | 16 | 55% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 17% |
| Arts and Humanities | 2 | 7% |
| Biochemistry, Genetics and Molecular Biology | 2 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Nursing and Health Professions | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 17 | 59% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2021.
All research outputs
#4,049,289
of 23,103,436 outputs
Outputs from International Journal of Hematology
#86
of 1,417 outputs
Outputs of similar age
#79,540
of 337,432 outputs
Outputs of similar age from International Journal of Hematology
#1
of 30 outputs
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So far Altmetric has tracked 1,417 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 93% of its peers.
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We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.