| Title |
The Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study: design, rationale, and methods
|
|---|---|
| Published in |
Sleep and Breathing, December 2015
|
| DOI | 10.1007/s11325-015-1254-3 |
| Pubmed ID | |
| Authors |
Brian B. Koo, Christine Won, Bernardo J. Selim, Li Qin, Sangchoon Jeon, Nancy S. Redeker, Dawn M. Bravata, Kingman P. Strohl, John Concato, Andrey V. Zinchuk, Henry K. Yaggi |
| Abstract |
The goal of the Determining Risk of Vascular Events by Apnea Monitoring (DREAM) study is to develop a prognostic model for cardiovascular outcomes, based on physiologic variables-related to breathing, sleep architecture, and oxygenation-measured during polysomnography in US veterans. The DREAM study is a multi-site, retrospective observational cohort study conducted at three Veterans Affairs (VA) centers (West Haven, CT; Indianapolis, IN; Cleveland, OH). Veterans undergoing polysomnography between January 1, 2000 and December 31, 2004 were included based on referral for evaluation of sleep-disordered breathing, documented history and physical prior to sleep testing, and ≥2-h sleep monitoring. Demographic, anthropomorphic, medical, medication, and social history factors were recorded. Measures to determine sleep apnea, sleep architecture, and oxygenation were recorded from polysomnography. VA Patient Treatment File, VA-Medicare Data, Vista Computerized Patient Record System, and VA Vital Status File were reviewed on dates subsequent to polysomnography, ranging from 0.06 to 8.8 years (5.5 ± 1.3 years; mean ± SD). The study population includes 1840 predominantly male, middle-aged veterans. As designed, the main primary outcome is the composite endpoint of acute coronary syndrome, stroke, transient ischemic attack, or death. Secondary outcomes include incidents of neoplasm, congestive heart failure, cardiac arrhythmia, diabetes, depression, and post-traumatic stress disorder. Laboratory outcomes include measures of glycemic control, cholesterol, and kidney function. (Actual results are pending.) CONCLUSIONS: This manuscript provides the rationale for the inclusion of veterans in a study to determine the association between physiologic sleep measures and cardiovascular outcomes and specifically the development of a corresponding outcome-based prognostic model. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 147 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 20 | 14% |
| Student > Ph. D. Student | 17 | 12% |
| Researcher | 16 | 11% |
| Student > Master | 15 | 10% |
| Other | 7 | 5% |
| Other | 24 | 16% |
| Unknown | 48 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 39 | 27% |
| Psychology | 16 | 11% |
| Neuroscience | 11 | 7% |
| Nursing and Health Professions | 7 | 5% |
| Computer Science | 4 | 3% |
| Other | 13 | 9% |
| Unknown | 57 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2015.
All research outputs
#17,778,101
of 22,834,308 outputs
Outputs from Sleep and Breathing
#794
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Outputs of similar age
#263,925
of 388,302 outputs
Outputs of similar age from Sleep and Breathing
#14
of 19 outputs
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