| Title |
Diseases and aging: Gender matters
|
|---|---|
| Published in |
Biochemistry, December 2015
|
| DOI | 10.1134/s0006297915120032 |
| Pubmed ID | |
| Authors |
V. A. Popkov, E. Yu. Plotnikov, D. N. Silachev, L. D. Zorova, I. B. Pevzner, S. S. Jankauskas, S. D. Zorov, V. A. Babenko, D. B. Zorov |
| Abstract |
At first glance, biological differences between male and female sex seem obvious, but, in fact, they affect a vast number of deeper levels apart from reproductive function and related physiological features. Such differences affect all organizational levels including features of cell physiology and even functioning of separate organelles, which, among other things, account for such global processes as resistance to diseases and aging. Understanding of mechanisms underlying resistance of one of the sexes to pathological processes and aging will allow taking into consideration gender differences while developing drugs and therapeutic approaches, and it will provide an opportunity to reproduce and enhance such resistance in the more vulnerable gender. Here we review physiological as well as cellular and biological features of disease course including aging that are affected by gender and discuss potential mechanisms behind these processes. Such mechanisms include features of oxidative metabolism and mitochondrial functioning. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 3% |
| Unknown | 28 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 24% |
| Researcher | 6 | 21% |
| Other | 2 | 7% |
| Student > Master | 2 | 7% |
| Student > Bachelor | 1 | 3% |
| Other | 3 | 10% |
| Unknown | 8 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 21% |
| Medicine and Dentistry | 4 | 14% |
| Biochemistry, Genetics and Molecular Biology | 3 | 10% |
| Business, Management and Accounting | 1 | 3% |
| Unspecified | 1 | 3% |
| Other | 2 | 7% |
| Unknown | 12 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2015.
All research outputs
#22,760,732
of 25,374,917 outputs
Outputs from Biochemistry
#21,450
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Outputs of similar age
#337,492
of 394,856 outputs
Outputs of similar age from Biochemistry
#129
of 141 outputs
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