| Title |
The peroxisome: an update on mysteries 2.0
|
|---|---|
| Published in |
Histochemistry and Cell Biology, September 2018
|
| DOI | 10.1007/s00418-018-1722-5 |
| Pubmed ID | |
| Authors |
Markus Islinger, Alfred Voelkl, H. Dariush Fahimi, Michael Schrader |
| Abstract |
Peroxisomes are key metabolic organelles, which contribute to cellular lipid metabolism, e.g. the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular redox balance. Peroxisomal dysfunction has been linked to severe metabolic disorders in man, but peroxisomes are now also recognized as protective organelles with a wider significance in human health and potential impact on a large number of globally important human diseases such as neurodegeneration, obesity, cancer, and age-related disorders. Therefore, the interest in peroxisomes and their physiological functions has significantly increased in recent years. In this review, we intend to highlight recent discoveries, advancements and trends in peroxisome research, and present an update as well as a continuation of two former review articles addressing the unsolved mysteries of this astonishing organelle. We summarize novel findings on the biological functions of peroxisomes, their biogenesis, formation, membrane dynamics and division, as well as on peroxisome-organelle contacts and cooperation. Furthermore, novel peroxisomal proteins and machineries at the peroxisomal membrane are discussed. Finally, we address recent findings on the role of peroxisomes in the brain, in neurological disorders, and in the development of cancer. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 20% |
| United Kingdom | 1 | 20% |
| Portugal | 1 | 20% |
| Germany | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 402 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 402 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 56 | 14% |
| Student > Bachelor | 54 | 13% |
| Researcher | 46 | 11% |
| Student > Master | 37 | 9% |
| Student > Doctoral Student | 19 | 5% |
| Other | 42 | 10% |
| Unknown | 148 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 132 | 33% |
| Agricultural and Biological Sciences | 37 | 9% |
| Medicine and Dentistry | 16 | 4% |
| Neuroscience | 13 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 2% |
| Other | 34 | 8% |
| Unknown | 161 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2022.
All research outputs
#971,907
of 24,217,893 outputs
Outputs from Histochemistry and Cell Biology
#5
of 926 outputs
Outputs of similar age
#21,691
of 341,266 outputs
Outputs of similar age from Histochemistry and Cell Biology
#1
of 27 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 926 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.